ArticleEthnicity & disease2020
Perceived Impediments to Completed Brain Autopsies Among Diverse Older Adults Who Have Signed a Uniform Anatomical Gift Act for Brain Donation for Clinical Research.
Article in Ethnicity & disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Organ Donation for Research Biobanking Among Historically Marginalized Racial and Ethnic Groups: A Systematic Review.JAMA network open · 2025Pooled it
- Autopsy findings in Alzheimer's disease clinical trial participants demonstrate a high frequency of off-target coexisting pathologic features.The journal of prevention of Alzheimer's disease · 2026Article
- Outreach, Recruitment and Engagement Cores of NIA-designated Alzheimer's Disease Research Centers: Current strategies and future directions.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Review
- Pathways to Racial/Ethnic Inequalities in Dementia.Annual review of clinical psychology · 2025Review
- Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Community recruitment of underrepresented populations to the AHEAD 3-45 preclinical AD trial using novel partnerships with nursing and community-based organizations: Lessons and outcomes.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Aging, Race, and Health Disparities: Recommendations From the Research Centers Collaborative Network.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- The neuropathological landscape of small vessel disease and Lewy pathology in a cohort of Hispanic and non-Hispanic White decedents with Alzheimer disease.Acta neuropathologica communications · 2024Article
- Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations.bioRxiv : the preprint server for biology · 2024Article
- Different cohort, disparate results: Selection bias is a key factor in autopsy cohorts.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- To donate, or not to donate, that is the question: Latino insights into brain donation.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- A Qualitative Examination of Knowledge, Experiences, and Considerations of PET Brain Scan Participation Among Older Black and Latino Adults.Journal of Alzheimer's disease : JAD · 2023Article
- Alzheimer disease in African American individuals: increased incidence or not enough data?Nature reviews. Neurology · 2022Review
- Brain Donation Decisions as Disease Specific Behaviors: An Elucidation of the Donation Process in the Context of Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2022Article
- Stability and change in acculturation-related characteristics in older Latinos: Implications for culturally compatible ADRD research.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Background: A small number of older adults in the United States who agree to brain donation for clinical research belong to diverse racial, ethnic, and economic groups. Those who agree, however, are less likely to have completed brain autopsies compared with older non-Latino Whites of higher socioeconomic status. As such, our understanding of Alzheimer's disease and related dementias remains limited in these underrepresented and understudied populations. Here, we examine perceived impediments to completed brain autopsies among diverse older adults who have agreed to brain donation for clinical research. Methods: Participants (N=22) were older adults (mean age=77 years) who self-identified as African American (n=8), Latino (n=6), or White of lower income (n=8). All participants had previously agreed to brain donation via the Uniform Anatomical Gift Act. Each participant took part in a one-time, semi-structured focus group. Data were analyzed using a Grounded Theory Approach with both Open Coding and Constant Comparative Coding. Results: Perceived impediments to completed brain autopsies varied by group. Older African Americans and older Latinos expressed concern about a lack of follow-through by family members regarding their brain donation wishes. Older Whites of lower income indicated that their own uncertainty surrounding the processes of brain donation and brain autopsy might serve as an impediment. Discussion: Diverse older adults expressed different perceived impediments to having brain autopsies completed upon their death. Continuous education for diverse older adults and their family members regarding brain donation for clinical research, including clear guidelines and processes, may facilitate completed brain autopsies among diverse older adults.
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