Evidence map›Paper›PMID 33250378›Full record

ArticleDrug and alcohol dependence2021

Marijuana, but not alcohol, use frequency associated with greater loneliness, psychological distress, and less flourishing among young adults.

Isaac C Rhew, Jennifer M Cadigan, Christine M Lee

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
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  5. The Longitudinal Relationship of Loneliness With Frequency and Problematic Use of Alcohol and Cannabis Among Young Adults.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article
  6. Article
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  8. Cannabis Use Among Adolescents and Young Adults with Cancer: A Scoping Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Review
  9. Momentary mindfulness versus distraction coping messages to reduce cannabis craving among young adults: A microrandomized trial.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  10. Article
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  13. Article
  14. Psychological Distress and Cannabis Vaping Among U.S. Adolescents.American journal of preventive medicine · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Trajectories of loneliness during COVID-19 pandemic and associations with mental health and substance use.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2023
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Isaac C RhewDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA. Electronic address: rhew@uw.edu.
Jennifer M CadiganDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Christine M LeeDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.

Funding

Developmental Models of High-Risk Alcohol Use & Social Roles in Young AdulthoodR01AA022087 · NIAAA · UNIVERSITY OF WASHINGTON · PI LEE, CHRISTINE M. · 2014 to 2018
$2.8M
Predictors and consequences of young adult marijuana use and concurrent and simultaneous alcohol use: Month to month variation across 24 consecutive monthsR01AA027496 · NIAAA · UNIVERSITY OF WASHINGTON · PI LEE, CHRISTINE M. · 2019 to 2021
$981k
NIAAA NIH HHS R01 AA022087NIAAA NIH HHS R01 AA027496
6 · The paper itself

Abstract

objectiveTo assess whether frequency of marijuana and alcohol use are cross-sectionally associated with indicators of social and emotional well-being including loneliness, psychological distress, and flourishing across important life domains among young adults.

methodThe study sample included 562 participants ages 22-29 who were originally recruited from an urban Pacific Northwest region in the US as part of a longitudinal study of social role transitions and alcohol use. At one assessment, participants completed an online survey that included a 3-item measure of loneliness, a 4-item measure of depression and anxiety symptoms, and a 12-item measure of flourishing as well as measures of marijuana and alcohol use frequency. Linear and generalized linear models were used to estimate associations of marijuana and alcohol use frequency with indicators of well-being.

resultsGreater frequency of marijuana use was associated with higher levels of loneliness, higher levels of psychological distress, and lower levels of flourishing, with the greatest difference observed for daily marijuana users compared to non-users. However, these indicators of well-being did not significantly differ by levels of alcohol use frequency.

conclusionStudy findings suggest that frequent users of marijuana, but not alcohol, may experience more loneliness, more psychological distress, and less flourishing. Intervention approaches for frequent marijuana users may be warranted to reduce impacts of loneliness and psychological distress and improve overall well-being.

Indexed as

Psychological DistressAdolescentAdultAlcohol DrinkingAnxietyCannabisEmotionsFemaleHumansLonelinessLongitudinal StudiesMaleMarijuana SmokingMarijuana UseMental HealthNorthwestern United StatesAlcoholFlourishingLonelinessMarijuanaPsychological distressYoung adulthood

Identifiers

PMID33250378
PMCPMC7792981

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.