ArticleJournal of the American Chemical Society2020
Enantioconvergent Amination of Racemic Tertiary C-H Bonds.
Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Ynimines as versatile precursors to 2-imido- and 2-amido-1,3-dienes for stereodivergent diels-alder reactions.Nature communications · 2026Article
- Silver-Catalyzed C(spACS organic & inorganic Au · 2026Review
- Copper-catalysed asymmetric cross-coupling reactions tolerant of highly reactive radicals.Nature chemistry · 2026Article
- Catalytic Metalloradical System for Radical 1,6-C(spJournal of the American Chemical Society · 2025Article
- Mechanistic and Computational Insights into Asymmetric Intramolecular Iron-Catalyzed Nitrene Transfer into Benzylic C─H Bonds.ACS catalysis · 2025Article
- Rhodium-Catalyzed Allylic Amination for the Enantioselective Synthesis of Tertiary β-Fluoroamines.Organic letters · 2025Article
- Metalloradical Catalysis: General Approach for Controlling Reactivity and Selectivity of Homolytic Radical Reactions.Angewandte Chemie (International ed. in English) · 2024Review
- Biocatalytic, Enantioenriched Primary Amination of Tertiary C-H Bonds.Nature catalysis · 2024Article
- Article
- Convergent synthesis of thiodiazole dioxides from simple ketones and amines through an unusual nitrogen-migration mechanism.Chemical science · 2023Article
- Catalytic, asymmetric carbon-nitrogen bond formation using metal nitrenoids: from metal-ligand complexesChemical science · 2023Review
- Metal-Catalyzed Enantioconvergent Transformations.Chemical reviews · 2023Review
- An iron(ii)-based metalloradical system for intramolecular amination of C(spChemical science · 2022Article
- Transition Metal Catalysis Controlled by Hydrogen Bonding in the Second Coordination Sphere.Chemical reviews · 2022Review
- Controlling Radical-Type Single-Electron Elementary Steps in Catalysis with Redox-Active Ligands and Substrates.JACS Au · 2021Review
- Nitrene transfer catalysts for enantioselective C-N bond formation.Nature reviews. Chemistry · 2021Review
- Revisiting the Electronic Structure of Cobalt Porphyrin Nitrene and Carbene Radicals with NEVPT2-CASSCF Calculations: Doublet versus Quartet Ground States.Inorganic chemistry · 2021Article
- Titanocene-Catalyzed [2+2] Cycloaddition of Bisenones and Comparison with Photoredox Catalysis and Established Methods.Angewandte Chemie (International ed. in English) · 2021Article
- Palladium/Xu-Phos-catalyzed asymmetric carboamination towards isoxazolidines and pyrrolidines.Chemical science · 2021Article
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4 authors.
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Abstract
Racemization is considered to be an intrinsic stereochemical feature of free radical chemistry as can be seen in traditional radical halogenation reactions of optically active tertiary C-H bonds. If the facile process of radical racemization could be effectively combined with an ensuing step of bond formation in an enantioselective fashion, then it would give rise to deracemizative functionalization of racemic tertiary C-H bonds for stereoselective construction of chiral molecules bearing quaternary stereocenters. As a demonstration of this unique potential in radical chemistry, we herein report that metalloradical catalysis can be successfully applied to devise Co(II)-based catalytic system for enantioconvergent radical amination of racemic tertiary C(sp
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