Evidence map›Paper›PMID 33249698›Full record

SynthesisJournal of thrombosis and haemostasis : JTH2021

Postinterventional antithrombotic management after venous stenting of the iliofemoral tract in acute and chronic thrombosis: A systematic review.

Pascale Notten, Hugo Ten Cate, Arina J Ten Cate-Hoek

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Journal of thrombosis and haemostasis : JTH, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Factors associated with patency loss after iliocaval and iliofemoral venous stenting.Journal of vascular surgery. Venous and lymphatic disorders · 2026
    Review
  5. The known, the unknown, and the covered stent: Lessons learned from iatrogenic iliac vein injuries.Journal of vascular surgery. Venous and lymphatic disorders · 2026
    Article
  6. Article
  7. Review
  8. Safety and Feasibility of the RevCore Catheter for Venous In-Stent Thrombosis: A Multicenter, Retrospective Study.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Deep venous stenting in females.CVIR endovascular · 2023
    Review
  16. Dual Therapy vs. Single Anticoagulation After Acute Deep Vein Thrombosis Iliac Stenting: A Doubly Robust Multicenter Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
  17. Chronic Venous Disease of the Lower Extremities: A State-of-the Art Review.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pascale NottenDepartment of Vascular Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID 0000-0002-8270-2000
Hugo Ten CateSchool for Cardiovascular Diseases, CARIM, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
Arina J Ten Cate-HoekSchool for Cardiovascular Diseases, CARIM, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
Maastricht University Medical Centre · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venous stenting has become a common treatment option for central deep venous outflow obstructions and postthrombotic syndrome. Following successful recanalization and stenting, stent patency is endangered by in-stent thrombosis and recurrent venous thromboembolism. Antithrombotic therapy might reduce patency loss. This systematic review summarizes the literature on antithrombotic therapy following (post)thrombotic venous stenting. A systematic PubMed, MEDLINE, EMBASE, and Cochrane search was performed for studies addressing antithrombotic therapy prescribed following venous stenting of the iliofemoral tract indicated by acute or chronic thrombotic pathology. A total of 277 articles was identified of which 64 (56 original studies) were selected. Overall, a mean primary patency rate of 82.3% was seen 1 year after the intervention, which decreased to 73.3% after 2 years. In the majority (43 of 56 studies, 77%), treatment was based on use of vitamin K antagonists, either with (18%) or without (59%) use of antiplatelet drugs. Only two studies (4%) directly assessed the effect of antithrombotic therapy on treatment outcomes. The impact of postinterventional antithrombotic therapy on stent patency remains unknown because of limited and insufficient data available in current literature. Further clinical research should more clearly address the role of antithrombotic therapy for preservation of long-term patency following venous stenting.

Indexed as

Postthrombotic SyndromeVenous ThrombosisFemoral VeinFibrinolytic AgentsHumansIliac VeinStentsTreatment OutcomeVascular PatencyFibrinolytic Agentsantithrombotic agentsdeep vein thrombosispostthrombotic syndromevascular patencyvenous stenting

Identifiers

PMID33249698
PMCPMC7986750
OpenAlexW3110394028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.