Evidence map›Paper›PMID 33249535›Full record

ArticleWorld journal of surgery2021

Perceptual Assessment and Acoustic Voice Analysis as Screening Tests for Vocal Fold Paresis After Thyroid or Parathyroid Surgery.

Maria Heikkinen, Elina Penttilä, Mari Qvarnström, Kimmo Mäkinen, Heikki Löppönen, Jussi M Kärkkäinen

Open access · hybridAbstract read
In one paragraph

Article in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maria HeikkinenDepartment of Otorhinolaryngology - Head & Neck Surgery, Kuopio University Hospital, PL 100, 70029, Kuopio, Finland. heikkinemk@gmail.com.ORCID http://orcid.org/0000-0001-6220-9932
Elina PenttiläDepartment of Otorhinolaryngology - Head & Neck Surgery, Kuopio University Hospital, PL 100, 70029, Kuopio, Finland.
Mari QvarnströmDepartment of Phoniatrics, Kuopio University Hospital, Kuopio, Finland.
Kimmo MäkinenInstitute of Clinical Medicine, University of Eastern, Kuopio, Finland.
Heikki LöppönenDepartment of Otorhinolaryngology - Head & Neck Surgery, Kuopio University Hospital, PL 100, 70029, Kuopio, Finland.
Jussi M KärkkäinenHeart Center, Kuopio University Hospital, Kuopio, Finland.
University of Eastern Finland · FIKuopio University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate the reliability of clinician-based perceptual assessment of voice and computerized acoustic voice analysis as screening tests for vocal fold paresis or paralysis (VFP) after thyroid and parathyroid surgery.

methodsThis was a prospective study of 181 patients undergoing thyroid or parathyroid procedure with pre and postoperative laryngoscopic vocal fold inspection, perceptual voice assessment using grade, roughness, breathiness, asthenia, and strain (GRBAS) scale and acoustic voice analysis using the multi-dimensional voice program (MDVP). Patients were divided into 2 groups for comparison; those with new postoperative VFP and those without. Potential screening tools were evaluated using the receiving operating characteristic (ROC) analysis.

resultsFourteen (6.6%) patients had a new postoperative VFP. Postoperative GRBAS scores were significantly (P < 0.05) higher in patients with VFP compared to those without. However, there were no statistically significant differences in MDVP values between the groups. Postoperative GRBAS grade score (cut off > 0) had the best sensitivity, 93%, for predicting VFP, but the specificity was only 50%. Postoperative jitter (cut off > 1.60) in MDVP had a good specificity, 90%, but only 50% sensitivity. Combining all the GRBAS and MDVP variables with P < 0.05 in the ROC analysis yielded a test with 100% sensitivity and 55% specificity.

conclusionsPhysician-based perceptual voice assessment has a high sensitivity for detecting postoperative VFP, but the specificity is poor. The risk of VFP is low in patients with completely normal voice at discharge. However, routine laryngoscopy after thyroid and parathyroid surgery is still the most reliable exam for VFP screening.

Indexed as

Thyroid GlandVocal CordsAcousticsAdultHumansParesisProspective StudiesReproducibility of Results

Identifiers

PMID33249535
PMCPMC7851023
OpenAlexW3107419988

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.