Evidence map›Paper›PMID 33249448›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2021

You Say Tomato, I Say Radish: Can Brief Cognitive Assessments in the U.S. Health Retirement Study Be Harmonized With Its International Partner Studies?

Lindsay C Kobayashi, Alden L Gross, Laura E Gibbons, Doug Tommet, R Elizabeth Sanders, Seo-Eun Choi, Shubhabrata Mukherjee, Maria Glymour, Jennifer J Manly, Lisa F Berkman and 3 more

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cognitive assessment tools for Arabic-speaking older adults: A systematic review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
  2. Effect of a cash transfer intervention on memory decline and dementia probability in older adults in rural South Africa.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Trial
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  8. Cognitive data harmonization across two racially diverse cohorts in the United States.Alzheimer's & dementia. Behavior & socioeconomics of aging · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lindsay C KobayashiCenter for Social Epidemiology and Population Health, Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor.
Alden L GrossDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health and Johns Hopkins University Center on Aging and Health, Baltimore, Maryland.
Laura E GibbonsDepartment of Medicine, School of Medicine, University of Washington, Seattle.
Doug TommetDepartment of Psychiatry and Human Behavior, Alpert Medical School, Brown University, Providence, Rhode Island.
R Elizabeth SandersDepartment of Medicine, School of Medicine, University of Washington, Seattle.
Seo-Eun ChoiDepartment of Medicine, School of Medicine, University of Washington, Seattle.
Shubhabrata MukherjeeDepartment of Medicine, School of Medicine, University of Washington, Seattle.
Maria GlymourDepartment of Epidemiology and Biostatistics, University of California, San Francisco.
Jennifer J ManlyDepartment of Neurology and the Taubman Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York.
Lisa F BerkmanHarvard Center for Population and Development Studies, Harvard T. H. Chan School of Public Health, Cambridge, Massachusetts.
Paul K CraneDepartment of Medicine, School of Medicine, University of Washington, Seattle.
Dan M MungasDepartment of Neurology, University of California, Davis, Sacramento.
Richard N JonesDepartment of Psychiatry and Human Behavior, Alpert Medical School, Brown University, Providence, Rhode Island.ORCID 0000-0002-1049-218X

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
THERAPEUTIC EFFECTS OF INTRA-NASAL INSULIN DETEMIRP50AG005136 · NIA · UNIVERSITY OF WASHINGTON · PI GRABOWSKI, THOMAS J. · 1985 to 2019
$57.2M
SOCIAL AND ECONOMIC PREDICTORS OF PHYSICAL AND COGNITIVE FUNCTIONP01AG041710 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI LISA F BERKMAN, THOMAS A GAZIANO · 2013 to 2026
$37.3M
University of Washington Alzheimer's Disease Research CenterP30AG066509 · NIA · UNIVERSITY OF WASHINGTON · PI Amanda D. Boyd · 2020 to 2026
$29.0M
Statistical Data EnclaveP30AG012846 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI A. FREEDMAN · 1999 to 2026
$23.2M
Psychometric Integrative Technology for Cognitive Health ResearchR01AG051170 · NIA · BROWN UNIVERSITY · PI JONES, RICHARD N · 2015 to 2019
$3.4M
Molecular mechanisms of Alzheimer's disease neuropathological endophenotypesK25AG055620 · NIA · UNIVERSITY OF WASHINGTON · PI MUKHERJEE, SHUBHABRATA · 2018 to 2022
$653k
Intersection of Physiologic Frailty and Cognitive Performance in Older Adults: An Integrative Data AnalysisK01AG050699 · NIA · JOHNS HOPKINS UNIVERSITY · PI GROSS, ALDEN L. · 2016 to 2020
$648k
NIA NIH HHS K01 AG050699NIA NIH HHS K25 AG055620NIA NIH HHS P01 AG041710NIA NIH HHS P30 AG012846NIA NIH HHS P30 AG066509NIA NIH HHS P50 AG005136NIA NIH HHS R01 AG051170NIA NIH HHS U01 AG009740NIH HHS R01AG051170
6 · The paper itself

Abstract

objectivesTo characterize the extent to which brief cognitive assessments administered in the population-representative U.S. Health and Retirement Study (HRS) and its International Partner Studies can be considered to be measuring a single, unidimensional latent cognitive function construct.

methodsCognitive function assessments were administered in face-to-face interviews in 12 studies in 26 countries (N = 155,690), including the U.S. HRS and selected International Partner Studies. We used the time point of the first cognitive assessment for each study to minimize differential practice effects across studies and documented cognitive test item coverage across studies. Using confirmatory factor analysis models, we estimated single-factor general cognitive function models and bifactor models representing memory-specific and nonmemory-specific cognitive domains for each study. We evaluated model fits and factor loadings across studies.

resultsDespite relatively sparse and inconsistent cognitive item coverage across studies, all studies had some cognitive test items in common with other studies. In all studies, the bifactor models with a memory-specific domain fit better than single-factor general cognitive function models. The data fit the models at reasonable thresholds for single-factor models in 6 of the 12 studies and for the bifactor models in all 12 of the 12 studies. DISCUSSION: The cognitive assessments in the U.S. HRS and its International Partner Studies reflect comparable underlying cognitive constructs. We discuss the assumptions underlying our methods, present alternatives, and future directions for cross-national harmonization of cognitive aging data.

Indexed as

CognitionCognitive AgingMemoryModels, StatisticalAdolescentAdultAgedAged, 80 and overFactor Analysis, StatisticalFemaleHealth SurveysHumansLongitudinal StudiesMaleMiddle AgedMulticenter Studies as TopicCognitive functionHealth surveyInternational comparisonItem response theoryStatistical harmonization

Identifiers

PMID33249448
PMCPMC8557836

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.