Evidence map›Paper›PMID 33249117›Full record

ArticleToxicology and applied pharmacology2021

Ozone-induced changes in oxidative stress parameters in brain regions of adult, middle-age, and senescent Brown Norway rats.

Prasada Rao S Kodavanti, Matthew Valdez, Judy E Richards, Datonye I Agina-Obu, Pamela M Phillips, Kimberly A Jarema, Urmila P Kodavanti

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology and applied pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  7. Peripheral HMGB1 is linked to OAlzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Prasada Rao S KodavantiNeurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Electronic address: kodavanti.prasada@epa.gov.
Matthew ValdezNeurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Judy E RichardsCardiopulmonary and Immunotoxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Datonye I Agina-ObuNeurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Pamela M PhillipsNeurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Kimberly A JaremaNeurological and Endocrine Toxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA.
Urmila P KodavantiCardiopulmonary and Immunotoxicology Branch, Public Health and Integrated Toxicology Division, CPHEA, ORD, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. Electronic address: kodavanti.prasada@epa.gov.
Environmental Protection Agency · US

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

A critical part of community based human health risk assessment following chemical exposure is identifying sources of susceptibility. Life stage is one such susceptibility. A prototypic air pollutant, ozone (O

Indexed as

Age FactorsAgingAnimalsBrainLocomotionMaleOxidative StressOzoneRatsRats, Inbred BNOzoneAgingAir pollutionAntioxidantsNeurotoxicityOxidative stressOzoneProtein carbonylsSusceptibility

Identifiers

PMID33249117
PMCPMC7775355
OpenAlexW3109615578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.