ArticleBehavioural brain research2021
A pilot study on amygdala volumetric changes among young adults with childhood maltreatment histories after a mindfulness intervention.
Article in Behavioural brain research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- PCC-hippocampal functional connectivity associated with stress biomarker changes after meditation training for healthy adults.Neuroscience letters · 2025Trial
- The neurobiological effects of childhood maltreatment on brain structure, function, and attachment.European archives of psychiatry and clinical neuroscience · 2025Review
- Neural propensity for trait rumination in adolescents: A cross-sectional study with Voxel-Based Morphometry.Journal of mood and anxiety disorders · 2025Article
- Mindfulness-based interventions for preventing childhood maltreatment and restoring health among survivors: a public health perspective.Mindfulness · 2025Article
- Neural correlates of reduction in self-judgment after mindful self-compassion training: A pilot study with resting state fMRI.Journal of mood and anxiety disorders · 2025Article
- Modulating mechanisms of adverse childhood experiences in a mindfulness-based intervention: preliminary insights from an opioid use disorder study.Frontiers in psychology · 2025Article
- Exploring the association between childhood trauma and limbic system subregion volumes in healthy individuals: a neuroimaging study.BMC psychiatry · 2024Article
- Temporal dynamics and long-term effects of a mindfulness-based intervention for young adults with adverse childhood experiences.Mindfulness · 2024Article
- Beneficial effects of mindfulness-based intervention on hippocampal volumes and episodic memory for childhood adversity survivors.Journal of affective disorders reports · 2024Article
- Childhood adversity severity modulates the associations between adaptive psychological changes and amygdala volumetric changes in response to behavioral interventions.Journal of affective disorders reports · 2024Article
- Measuring types and timing of childhood maltreatment: The psychometric properties of the KERF-40.PloS one · 2022Article
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Authors and funding
4 authors.
Funding
Abstract
The amygdala morphometry is highly sensitive to stress and is implicated in various psychopathologies that are common among individuals with childhood maltreatment histories. This pilot study investigated bilateral amygdala volumetric changes among 15 young adults with childhood maltreatment histories undergoing an eight-week mindfulness intervention compared to 19 matched participants in a waitlist control group. Results indicated significant cross-individual variability in amygdala volumetric changes after the intervention, which resulted in no significant group by time interaction effect. Degree and direction of changes in right amygdala volume correlated with baseline volumes, with larger than average right amygdala showing an increase in volume and smaller amygdala a decrease. Increasing right amygdala volume was also associated with higher intervention compliance, and a greater increase in self-compassion. Increasing left amygdala volume was associated with more reduction in perceived stress, rejection sensitivity and interpersonal distress. Findings from the present study highlight the importance of investigating individual variability and its contributing factors in future studies on neural responses of mindfulness interventions, as well as the distinct responses of the left and right amygdala.
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