Evidence map›Paper›PMID 33248684›Full record

ArticleAmerican journal of surgery2021

Factors associated with physicians' recommendations for managing low-risk papillary thyroid cancer.

Alexandria D McDow, Benjamin R Roman, Megan C Saucke, Catherine B Jensen, Nick Zaborek, Jamia Linn Jennings, Louise Davies, Juan P Brito, Susan C Pitt

Abstract read
In one paragraph

Article in American journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Differences in health state valuation for small, low-risk thyroid cancer between general population and cancer survivors: a cross-sectional analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
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  13. Review
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  16. Peace of Mind: A Role in Unnecessary Care?Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexandria D McDowDivision of Surgery Oncology, Department of Surgery, Indiana University School of Medicine, 545 Barnhill Drive EH 537, Indianapolis, IN, 46202, USA. Electronic address: amcdow@iu.edu.
Benjamin R RomanDivision of Head and Neck, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA. Electronic address: romanb@mskcc.org.
Megan C SauckeDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave., Madison, WI, 53792, USA. Electronic address: saucke@surgery.wisc.edu.
Catherine B JensenDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave., Madison, WI, 53792, USA. Electronic address: cjensen22@wisc.edu.
Nick ZaborekDepartment of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave., Madison, WI, 53792, USA. Electronic address: zaborek@wisc.edu.
Jamia Linn JenningsWisconsin Department of Health Services, 1 West Wilson Street, Madison, WI, 53703, USA. Electronic address: jamia.jennings@dhs.wisconsin.gov.
Louise DaviesThe VA Outcomes Group, Department of Veterans Affairs Medical Center, White River Junction, VT, USA and The Dartmouth Institute for Health Policy and Clinical Practice, Hanover, NH, 1 Medical Center Drive, Lebanon, NH, 03756, USA. Electronic address: Louise.Davies@dartmouth.edu.
Juan P BritoDivision of Diabetes, Endocrinology, Metabolism, and Nutrition, Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. Electronic address: Brito.Juan@mayo.edu.
Susan C PittDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave., Madison, WI, 53792, USA. Electronic address: pitt@surgery.wisc.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Impact of Emotions on Treatment Decisions About Low-Risk Thyroid CancerK08CA230204 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI PITT, SUSAN C · 2018 to 2023
$1.4M
NCI NIH HHS K08 CA230204NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

backgroundThe 2015 American Thyroid Association endorsed less aggressive management for low-risk papillary thyroid cancer (LR-PTC). We aimed to identify factors influencing physicians' recommendations for LR-PTC.

methodsWe surveyed members of three professional societies and assessed respondents' recommendations for managing LR-PTC using patient scenarios. Multivariable logistic regression models identified clinical and non-clinical factors associated with recommending total thyroidectomy (TT) and active surveillance (AS).

resultsThe 345 respondents included 246 surgeons and 99 endocrinologists. Physicians' preference for their own management if diagnosed with LR-PTC had the strongest association with their recommendation for TT and AS (TT: OR 12.3; AS: OR 7.5, p < 0.001). Physician specialty and stated patient preference were also significantly associated with their recommendations for both management options. Respondents who received information about AS had increased odds of recommending AS.

conclusionsPhysicians' recommendations for LR-PTC are strongly influenced by non-clinical factors, such as personal treatment preference and specialty.

Indexed as

AdultAgedAge FactorsClinical Decision-MakingComorbidityEndocrinologistsFemaleHumansMaleMedical OveruseMiddle AgedPatient PreferencePractice Patterns, Physicians'Risk AssessmentSurgeonsSurveys and QuestionnairesActive surveillanceLow-riskOvertreatmentSurveyThyroid cancerThyroidectomy

Identifiers

PMID33248684
PMCPMC8262457

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.