Evidence map›Paper›PMID 33248573›Full record

ArticlePoultry science2020

Yeast cell wall product enhanced intestinal IgA response and changed cecum microflora species after oral vaccination in chickens.

S Bi, J Zhang, Y Qu, B Zhou, X He, J Ni

Open access · goldAbstract read
In one paragraph

Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Probiotics as Potential Enhancers of Veterinary Vaccines.Probiotics and antimicrobial proteins · 2026
    Review
  2. Field Studies on theVeterinary sciences · 2026
    Article
  3. Article
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  6. Effects of dietary supplementation ofFrontiers in veterinary science · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

S BiDepartment of Veterinary Medicine, College of Veterinary Medicine, Southwest University, Rongchang, Chongqing 402460, PR China.
J ZhangDepartment of Veterinary Medicine, College of Veterinary Medicine, Southwest University, Rongchang, Chongqing 402460, PR China.
Y QuDepartment of Veterinary Medicine, College of Veterinary Medicine, Southwest University, Rongchang, Chongqing 402460, PR China.
B ZhouDepartment of Veterinary Medicine, College of Veterinary Medicine, Southwest University, Rongchang, Chongqing 402460, PR China.
X HeDepartment of Veterinary Medicine, College of Veterinary Medicine, Southwest University, Rongchang, Chongqing 402460, PR China.
J NiImmunology Research Center, Medical Research Institute, Southwest University, Rongchang, Chongqing 402460, PR China. Electronic address: Nijingxuan@swu.edu.cn.
Southwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study was designed to explore the effect of a commercial yeast cell wall product (YP) on chicken intestinal IgA response and cecum microbiome after oral vaccination. Chickens were fed with YP during the experiments and orally immunized with live Newcastle disease virus (NDV) vaccine at 2 wk of age. Then, the animals were sacrificed, and samples were collected to measure the indicators of hemagglutination inhibition (HI), IgA response, IgA + cells, and cecum microbiome populations. The results showed that supplement of YP significantly enhanced serum NDV HI titer, intestinal NDV-specific secretory IgA, and intestinal IgA + cells. The sequencing results revealed that obviously increased relative abundance of Ruminococcaceae and decreased population of Bacteroidaceae in cecum were found in YP group. In summary, YP supplementation in diet enhanced intestinal IgA response to NDV vaccination by oral route and modulated the cecum microbiota to the advantage of the host in chickens.

Indexed as

CecumCell WallNewcastle DiseasePoultry DiseasesViral VaccinesYeastsAnimalsAntibodies, ViralChickensGastrointestinal MicrobiomeImmunityImmunoglobulin ANewcastle disease virusVaccinationAntibodies, ViralImmunoglobulin AViral Vaccinescecum microfloraintestinal IgA responseNewcastle disease virus vaccineyeast cell wall product

Identifiers

PMID33248573
PMCPMC7705035
OpenAlexW3092519840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.