Evidence map›Paper›PMID 33248572›Full record

ArticlePoultry science2020

Influence of Lacto-Immuno-Vital on growth performance and gene expression of IgA, MUC-2, and growth factor IGF-2 in the jejunum of broiler chickens.

M Levkut, V Karaffová, M Levkutová, V Seman, V Revajová, Z Ševčíková, R Herich, M Levkut

Open access · goldAbstract read
In one paragraph

Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. The Effect ofLife (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

M LevkutDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic.
V KaraffováDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic. Electronic address: viera.karaffova@uvlf.sk.
M LevkutováDepartment of Epizootiology, Parasitology and Protection of One Health, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic.
V SemanRegional Association of Veterinary Doctors, Trebišov, Slovak Republic.
V RevajováDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic.
Z ŠevčíkováDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic.
R HerichDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic.
M LevkutDepartment of Morphological Disciplines, University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic; Neuroimmunological Institute SAS, Bratislava, Slovak Republic.
University of Veterinary Medicine in Košice · SKMorpho (United States) · USState Veterinary Administration · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of Lacto-Immuno-Vital synbiotic preparation on gene expression of IgA, MUC-2, and growth factor IGF-2 in the jejunum and on BW gain in broiler chickens were studied. A flock of 64,400 1-day-old Hybrid ROSS 308 chickens was inducted in the 42-day experiment. The chickens were divided into 2 equally size groups in separate halls. The chickens in the experimental (E) group received 500 g of Lacto-Immuno-Vital in 1,000 L of drinking water. The preparation was administered daily from the first day (day 1) to day 7 of the experiment. From day 7 to day 22, it was given in pulsed manner (every third day) at a dose of 300 g in 1,000 L of drinking water. The broiler chickens in the E group gained more weight (P < 0.001) compared with control from day 10 to day 42. Death of animals during feeding period was 1,078 chickens in the E group compared with 1,115 dead chickens in the control group. Feed conversion ratio was 1.61 kg of supplemented diet/kg of BW in the E group compare with 1.67 kg of nonsupplemented diet/kg of BW in control. The relative expression of IgA gene in the jejunum was upregulated on day 22 in the E group compared with control (P < 0.05), whereas relative expression of MUC-2 gene was upregulated in the E group compared with control on day 8 and day 22 (P < 0.05; P < 0.001). Similarly, relative expression of IGF-2 gene was upregulated in the E group compared with control on both samplings (P < 0.01). The composition of Lacto-Immuno-Vital synbiotic preparation showed beneficial effects on growth performance, feed conversion ratio, morbidity, mortality, and selected parameters of mucosal immunity in the chicken jejunum.

Indexed as

ChickensDietary SupplementsJejunumProbioticsAnimalsDietGene ExpressionImmunoglobulin AInsulin-Like Growth Factor IIMucin-2Immunoglobulin AInsulin-Like Growth Factor IIMucin-2broilergrowth factorIgamucinsynbiotic preparation

Identifiers

PMID33248572
PMCPMC7705053
OpenAlexW3091608942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.