Evidence map›Paper›PMID 33248562›Full record

ArticlePoultry science2020

Chondronecrosis with osteomyelitis in broilers: further defining a bacterial challenge model using standard litter flooring and protection with probiotics.

Adnan A K Alrubaye, Nnamdi S Ekesi, Amer Hasan, Dawn A Koltes, Robert F Wideman, Douglas D Rhoads

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Poultry science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
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  7. Article
  8. Article
  9. Virulence Mechanisms of Staphylococcal Animal Pathogens.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Review on skeletal disorders caused byThe veterinary quarterly · 2022
    Review
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Adnan A K AlrubayeCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR, USA; Department of Biological Sciences, University of Arkansas, Fayetteville, AR, USA; Department of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Nnamdi S EkesiCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR, USA; Department of Biological Sciences, University of Arkansas, Fayetteville, AR, USA.
Amer HasanCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR, USA; Department of Biological Sciences, University of Arkansas, Fayetteville, AR, USA; Department of Veterinary Public Health, College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq.
Dawn A KoltesDepartment of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Robert F WidemanCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR, USA; Department of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Douglas D RhoadsCell and Molecular Biology Program, University of Arkansas, Fayetteville, AR, USA; Department of Biological Sciences, University of Arkansas, Fayetteville, AR, USA. Electronic address: drhoads@uark.edu.
University of Arkansas at Fayetteville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report demonstrates that high levels of lameness can be induced by a limited bacterial challenge in drinking water for birds raised on litter flooring, comparable with lameness induced by the gold standard for inducing lameness, growth on suspended wire flooring. The bacterium used in the challenge was cultured from lesions in birds induced for bacterial chondronecrosis with osteomyelitis (BCO) in the wire-flooring model so the epidemiology appears similar. The litter-flooring model could better approximate broiler operations. Furthermore, the work demonstrates that 2 commercial probiotics (GalliProTect and GalliProMax) can reduce lameness in the bacterial challenge litter-flooring model. Lameness attributable to BCO is one of the most significant animal welfare issues for broiler production. The wire-flooring and litter-flooring models afford alternatives for understanding the etiology, and epidemiology of BCO, and development of management strategies to reduce lameness. Probiotics afford a promising management strategy. The results suggest that the probiotic protection may extend beyond just intestinal health and intestinal barrier function.

Indexed as

Bacterial InfectionsChickensNecrosisOsteomyelitisPoultry DiseasesProbioticsAnimalsFloors and FloorcoveringsLameness, AnimalbacteriabroilerchondronecrosislamenessStaphylococcus

Identifiers

PMID33248562
PMCPMC7704996
OpenAlexW3087632523

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.