Evidence map›Paper›PMID 33247948›Full record

ArticleBritish journal of pharmacology2021

Activation of trace amine-associated receptor 1 selectively attenuates the reinforcing effects of morphine.

Jianfeng Liu, Robert Seaman, Bernard Johnson, Ruyan Wu, Jimmy Vu, Jingwei Tian, Yanan Zhang, Jun-Xu Li

Open access · bronzeAbstract read
In one paragraph

Article in British journal of pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Trace amine-associated receptor 1 and drug abuse.Advances in pharmacology (San Diego, Calif.) · 2022
    Article
  6. Potential therapeutic targets for the treatment of opioid abuse and pain.Advances in pharmacology (San Diego, Calif.) · 2022
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jianfeng LiuDepartment of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York, USA.
Robert SeamanDepartment of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York, USA.
Bernard JohnsonDepartment of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York, USA.ORCID 0000-0002-3152-737X
Ruyan WuDepartment of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York, USA.
Jimmy VuDepartment of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York, USA.
Jingwei TianSchool of Pharmacy, Yantai University, Yantai, China.
Yanan ZhangResearch Triangle Institute, Research Triangle Park, North Carolina, USA.
Jun-Xu LiDepartment of Pharmacology and Toxicology, University at Buffalo, Buffalo, New York, USA.ORCID 0000-0003-4749-0767
University at Buffalo, State University of New York · USRTI International · USYantai University · CN

Funding

TAAR1 agonists for nicotine addictionR01DA047967 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LI, JUN-XU · 2019 to 2023
$2.0M
TAAR 1 modulation of addiction-related effects of nicotineR21DA040777 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LI, JUN-XU · 2016 to 2017
$479k
NIDA NIH HHS R01 DA047967NIDA NIH HHS R21 DA040777
6 · The paper itself

Abstract

background and purposeTrace amine-associated TA EXPERIMENTAL APPROACH: Effects of the selective TA KEY

resultsRO5263397 attenuated the expression of morphine-induced behavioural sensitization in wildtype but not TA CONCLUSION AND IMPLICATIONS: These results indicated that TA

Indexed as

MorphineMorphine DependenceAnimalsDose-Response Relationship, DrugMaleMiceRatsReceptors, G-Protein-CoupledReinforcement, PsychologyTrace Amine-Associated ReceptorsMorphineReceptors, G-Protein-CoupledTrace Amine-Associated Receptorsanalgesiamorphinereinforcing effectsTA1 receptorwithdrawal

Identifiers

PMID33247948
PMCPMC8758336
OpenAlexW3110597512

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.