Evidence map›Paper›PMID 33247825›Full record

ArticleMaternal and child health journal2021

Birth Weight and Maternal Body Size as Determinants of Blood Pressure at Age 17: Results from the Jerusalem Perinatal Study Cohort.

Uri P Dior, Gilad Karavani, Michael Bursztyn, Ora Paltiel, Ronit Calderon-Margalit, Yechiel Friedlander, Iaroslav Youssim, Orly Manor, Hagit Hochner

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Article in Maternal and child health journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Uri P DiorBraun School of Public Health, The Hebrew University-Hadassah Medical Center, Jerusalem, Israel. uri.dior@gmail.com.ORCID http://orcid.org/0000-0002-1130-7791
Gilad KaravaniDepartment of Obstetrics and Gynecology, Hadassah Medical Center and Hebrew University-Hadassah Medical School, P.O. Box 12000, 91120, Jerusalem, Israel.ORCID http://orcid.org/0000-0003-1848-4560
Michael BursztynHypertension Unit, Department of Medicine, The Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Ora PaltielBraun School of Public Health, The Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Ronit Calderon-MargalitBraun School of Public Health, The Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Yechiel FriedlanderBraun School of Public Health, The Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Iaroslav YoussimBraun School of Public Health, The Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Orly ManorBraun School of Public Health, The Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Hagit HochnerBraun School of Public Health, The Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Hadassah Medical Center · IL

Funding

NIH HHS 2R01CA7080197-07
6 · The paper itself

Abstract

objectivesTo investigate the effect of birth weight (BW) and maternal pre-pregnancy BMI (mBMI) on blood pressure (BP) in adolescence.

methodsA Population-based cohort of 11,729 births in Jerusalem during 1974-1976, with archival data on maternal and birth characteristics was performed. Measurements at age 17 were assessed and linear regression models were used to evaluate the associations of birth characteristics with BP outcomes.

resultsBW was inversely associated with both systolic (SBP) and diastolic (DBP) BP at age 17 (SBP: B = - 0.829, p = 0.002; DBP: B = - 0.397, p = 0.033). The interaction term between BW and weight at age 17 was significant for DBP (p = 0.017) and pulse pressure (p = 0.005). mBMI yielded significant positive associations with BP, independent of BW. CONCLUSIONS FOR PRACTICE: Our findings indicate that there are at least two distinct pathways linking early life characteristics with subsequent BP: Intrauterine growth, as reflected by BW and other genetic or environmental factors, reflected by mBMI and maternal education, contribute to offspring adolescent BP. These results warrant replication in other birth cohorts and underline the need to explore specific mechanisms that account for these associations.

Indexed as

Birth WeightAdolescentAdultAnthropometryAtherosclerosisBlood PressureBody Mass IndexBody SizeCohort StudiesFemaleHumansIsraelMalePregnancyPregnancy in ObesityArterialAtherosclerosisBirth weightBlood pressure

Identifiers

PMID33247825
OpenAlexW3110365984

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.