Evidence map›Paper›PMID 33247793›Full record

ArticleDigestive diseases and sciences2021

Methanogen Abundance Thresholds Capable of Differentiating In Vitro Methane Production in Human Stool Samples.

Levi Teigen, Prince P Mathai, Michael Matson, Sharon Lopez, Daria Kozysa, Amanda J Kabage, Matthew J Hamilton, Byron P Vaughn, Michael J Sadowsky, Alexander Khoruts

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Article in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Journal of oral microbiology · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Levi Teigen *Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, 55455, USA.
Prince P Mathai *Biotechnology Institute, University of Minnesota, St. Paul, MN, 55108, USA.
Michael MatsonDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, 55455, USA.
Sharon LopezDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, 55455, USA.
Daria KozysaDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, 55455, USA.
Amanda J KabageDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, 55455, USA.
Matthew J HamiltonBiotechnology Institute, University of Minnesota, St. Paul, MN, 55108, USA.
Byron P VaughnDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, 55455, USA.
Michael J Sadowsky *Biotechnology Institute, University of Minnesota, St. Paul, MN, 55108, USA.
Alexander Khoruts *Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, 55455, USA. khoru001@umn.edu.ORCID 0000-0002-3205-3188
University of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntestinal methane (CH

aimsIn this study, taxonomic and functional gene analyses and in vitro CH

methodsWe performed a cross-sectional study involving full stool samples collected from 33 healthy individuals. In vitro CH

resultsMethanobrevibacter was found to be the most abundant methane producer and its relative abundance provides a clear distinction between CH

conclusionGiven the decreased time-burden placed on patients, a qPCR-based test on a fecal sample can become a valuable tool in clinical assessment of CH

Indexed as

BacteriaDNA, ArchaealDNA, BacterialEuryarchaeotaFecesHumansMethaneMethanobacterialesSpecies SpecificityDNA, ArchaealDNA, BacterialMethaneAmplicon sequencingGut microbiotamcrA geneMethaneMethanobrevibacterMethanogensMolecular thresholdsQuantitative PCR

Identifiers

PMID33247793
OpenAlexW3107782078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.