Evidence map›Paper›PMID 33247768›Full record

ArticleAbdominal radiology (New York)2021

Liver cT

Arjun N A Jayaswal, Christina Levick, Jane Collier, Elizabeth M Tunnicliffe, Matthew D Kelly, Stefan Neubauer, Eleanor Barnes, Michael Pavlides

2 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in Abdominal radiology (New York), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06144827 nawithdrawnnot on this mapstarted 2025, after this paper: background citation

Pilot Study to Assess the Role of Blood-based Biomarkers and Quantitative MR Imaging for Patients Receiving Radiation Therapy for Liver Cancer

TypeinterventionalSponsorMontefiore Medical CenterRan2025 to 2028Enrolled0ConditionsCancer, Hepatocellular, Radiotherapy Side EffectArmsMultiparametric MRI scans, Multiparametric MRI scans + HepQuantShunt Test
NCT06899152 narecruitingnot on this mapstarted 2025, after this paper: background citation

HepQuant: Pilot Study to Assess the Role of Blood-based Biomarkers and Quantitative MR Imaging for Patients Receiving Radiation Therapy for Liver Cancer

TypeinterventionalSponsorMontefiore Medical CenterRan2025 to 2031Enrolled40ConditionsLiver Cancer, Hepatocellular Carcinoma, Hepatocellular Cancer, CholangiocarcinomaArmsHepQuant DuO, Multiparametric MRI Scans
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Practical applications of AI in body imaging.Abdominal radiology (New York) · 2026
    Review
  2. T1 Mapping of the Abdomen, From theAJR. American journal of roentgenology · 2025
    Review
  3. Accurate and precise in vivo liver 3D TMagnetic resonance in medicine · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Arjun N A JayaswalOxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-3272-2695
Christina LevickOxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0003-3306-7482
Jane CollierTranslational Gastroenterology Unit, University of Oxford, Oxford, UK.
Elizabeth M TunnicliffeOxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-6945-5201
Matthew D KellyPerspectum Ltd, Oxford, UK.
Stefan NeubauerOxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Eleanor Barnes *Translational Gastroenterology Unit, University of Oxford, Oxford, UK.ORCID 0000-0002-0860-0831
Michael Pavlides *Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. michael.pavlides@cardiov.ox.ac.uk.ORCID 0000-0001-9882-8874
John Radcliffe Hospital · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDirect-acting antiviral therapies (DAAs) for treatment of chronic hepatitis C virus (HCV) have excellent rates of viral eradication, but their effect on regression of liver fibrosis is unclear. The primary aim was to use magnetic resonance imaging (MRI) and spectroscopy (MRS) to evaluate changes in liver fibrosis, liver fat and liver iron content (LIC) in patients with chronic HCV following treatment with DAAs.

methodsIn this prospective study, 15 patients with chronic HCV due to start treatment with DAAs and with transient elastography (TE) > 8 kPa were recruited consecutively. Patients underwent MRI and MRS at baseline (before treatment), and at 24 weeks and 48 weeks after the end of treatment (EoT) for the measurement of liver cT

resultsAll patients achieved a sustained virological response. Liver cT

conclusionLiver cT

Indexed as

Antiviral AgentsHepatitis C, ChronicHumansLiver CirrhosisProspective StudiesSustained Virologic ResponseAntiviral AgentsDirect-acting antiviralsHepatitis C virusIron corrected T1T1 mapping

Identifiers

PMID33247768
PMCPMC8131342
OpenAlexW3107290042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.