Evidence map›Paper›PMID 33247617›Full record

ArticleJournal of veterinary internal medicine2021

Clinical features of muscle cramp in 14 dogs.

Teresa Gagliardo, Roberta Ruggeri, Andrea Di Paola, Massimo Baroni, Giunio B Cherubini, Antonella Gallucci, Cristian Falzone, Stefania Trimboli, Andrey Albul, Gualtiero Gandini

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Clinical features of muscle cramp in 14 dogs.Journal of veterinary internal medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 6 countries.

Teresa GagliardoDepartment of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0002-6566-6423
Roberta RuggeriDepartment of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Andrea Di PaolaDepartment of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Massimo BaroniClinica Veterinaria Valdinievole Monsummano Terme, Pistoia, Italy.
Giunio B CherubiniDepartment of Neurology and Neurosurgery, Dick White Referrals, Six Mile Bottom, United Kingdom.
Antonella GallucciCentro Veterinario Professionale La Fenice, Cagliari, Italy.
Cristian FalzoneDiagnostica Piccoli Animali, Vicenza, Italy.
Stefania TrimboliAmbulatorio Veterinario Trimboli, Messina, Italy.
Andrey AlbulVeterinary Hospital of Neurology, Traumatology and Intensive Care, Saint-Petersburg, Russia.
Gualtiero GandiniDepartment of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
University of Bologna · ITCity Hospital No. 40 · RUClínica Santa María · CODepartment of Animal Health · VNTrimble (Germany) · DEVeterinary Oncological Center · ITWhite Clinic · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMuscle cramps (MCs) are prolonged, involuntary, painful muscle contractions characterized by an acute onset and short duration, caused by peripheral nerve hyperactivity.

objectivesTo provide a detailed description of the clinical features and diagnostic findings in dogs affected by MCs. ANIMALS: Fourteen dogs.

methodsMulticenter retrospective case series. Cases were recruited by a call to veterinary neurologists working in referral practices. Medical records and videotapes were searched for dogs showing MCs. The follow-up was obtained by telephone communication with the owner and the referring veterinarian.

resultsThree patterns of presentation were identified depending on the number of affected limbs and presence/absence of migration of MCs to other limbs. In 9/14 (64%) of dogs, MCs were triggered by prompting the dogs to move. 8/14 (58%) dogs were overtly painful with 6/14 (42%) showing mild discomfort. The cause of MCs was hypocalcemia in 11/14 (79%) dogs: 9 dogs were affected by primary hypoparathyrodism, 1 dog by intestinal lymphoma and 1 dog by protein losing enteropathy. In 3/14 cases (21%) the cause was not identified, and all 3 dogs were German Shepherds. CONCLUSIONS AND CLINICAL IMPORTANCE: Muscle cramps can manifest in 1 of 3 clinical patterns. Muscle cramps are elicited when dogs are encouraged to move and do not always appear as painful events, showing in some cases only discomfort. The main cause of MCs in this study was hypocalcemia consequent to primary hypoparathyroidism. In dogs having MCs of unknown etiology, idiopathic disease or paroxysmal dyskinesia could not be ruled out.

Indexed as

Dog DiseasesHypocalcemiaProtein-Losing EnteropathiesAnimalsDogsMuscle CrampRetrospective Studiescaninehypocalcemiahypoparathyroidismmuscle cramps

Identifiers

PMID33247617
PMCPMC7848340
OpenAlexW3107518622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.