Evidence map›Paper›PMID 33247587›Full record

ReviewChemical senses2020

Laryngeal Chemoreflex in Health and Disease: A Review.

Shivani Pathak, Laurie Slovarp, Matthew S Clary, Marie E Jetté

Open access · greenAbstract readReview
In one paragraph

Review in Chemical senses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. A systematic review of HRV during diving in very cold water.International journal of circumpolar health · 2023
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Examining the Influence of Chemosensation on Laryngeal Health and Disorders.Journal of voice : official journal of the Voice Foundation · 2023
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shivani PathakDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado, Aurora, CO, USA.
Laurie SlovarpSchool of Speech, Language, Hearing, & Occupational Sciences, University of Montana, Missoula, MT, USA.
Matthew S ClaryDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado, Aurora, CO, USA.
Marie E JettéDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado, Aurora, CO, USA.
University of Colorado Anschutz Medical Campus · USUniversity of Montana · US

Funding

Institutional Training in Otolaryngology ResearchT32DC012280 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI Yuri Agrawal, Sue C. Kinnamon · 2013 to 2026
$3.4M
Role of taste signaling in airway epithelial functionK23DC014747 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI RAMAKRISHNAN, VIJAY · 2015 to 2020
$1.2M
NIDCD NIH HHS K23 DC014747NIDCD NIH HHS T32 DC012280
6 · The paper itself

Abstract

The larynx plays a key role in airway protection via the laryngeal chemoreflex (LCR). This involuntary reflex can be evoked when hazardous substances activate mucosal receptors, which send signals to be processed within the brainstem. Although the LCR is meant to be protective, the reflex can become hyperstimulated, even to benign stimuli, which can result in pathological disorders, such as chronic cough and inducible laryngeal obstruction. In this review, we will outline the mechanism of the LCR and its associated pathological disorders.

Indexed as

Airway ObstructionAnimalsApneaBrain StemChemoreceptor CellsCoughHumansLaryngeal NervesLarynxReflexRespiration Disordersairway receptorschemoreflexcoughlarynx

Identifiers

PMID33247587
PMCPMC7718607
OpenAlexW3107559229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.