Evidence map›Paper›PMID 33247377›Full record

Observational studyIndian journal of pediatrics2021

Post Vaccination Epidemiology and Genotyping of Rotavirus Gastroenteritis at a Tertiary Care Centre of North-East Rajasthan.

R K Gupta, Shailja Vajpayee, Ruchi Agrawal, Alok Kumar Goyal, Nayana P Nair, Varunkumar Thiyagarajan

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Indian journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.0field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Information for Action: The Power of Surveillance.Indian journal of pediatrics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

R K GuptaDepartment of Pediatric Medicine, SMS Medical College, Jaipur, Rajasthan, India.
Shailja VajpayeeDepartment of Pediatric Medicine, SMS Medical College, Jaipur, Rajasthan, India.
Ruchi AgrawalDepartment of Pathology, SMS Medical College, Jaipur, Rajasthan, India.
Alok Kumar GoyalDepartment of Pediatric Medicine, SMS Medical College, Jaipur, Rajasthan, India. goyalalok916@gmail.com.
Nayana P NairWellcome Trust Research Laboratory, Christian Medical College, Vellore, Tamil Nadu, India.
Varunkumar ThiyagarajanWellcome Trust Research Laboratory, Christian Medical College, Vellore, Tamil Nadu, India.
Sawai ManSingh Medical College and Hospital · INChristian Medical College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo estimate the proportion of rotavirus diarrhea among hospitalized children aged under-five years, to determine the circulating rotavirus genotypes and to know impact rotavirus vaccine on prevalence and severity of rotavirus diarrhea.

methodsThis study was a hospital based cross-sectional observational study conducted over a period of 29 mo (September 2017 through January 2020). Stool samples were collected from children who fall within the age range of 0-59 mo with acute diarrhea attending emergency or needing admission. Stool samples were tested for rotavirus by the enzyme linked immune-sorbent assay (ELISA) and genotyped using published methods.

resultsOut of 1480 samples, 360 (24.32%) cases were positive for rotavirus by ELISA, majority of them were male (62.97%). Maximum rotavirus positivity was found in the age group of <11 mo (55.27%). Statistically significance difference was seen in episodes of diarrhea and experience of vomiting in rotavirus diarrhea cases. Highest prevalence has been seen during winter season. The most prevalent G and P type combinations were G3P [8] strains [122 (34.08%)], G2P [4] [83 (23.18%)], G1P [8] [27 (7.54%)] and G9P [4] [20 (5.59%)]. Mixed strains contribute a significant proportion of stool sample.

conclusionsRotavirus is an important cause of diarrhea in hospitalized children. There is continued circulation of G9 and G12 strains and the emergence of G3P [8] as most common strain.

Indexed as

GastroenteritisRotavirusRotavirus InfectionsChildCross-Sectional StudiesDiarrheaFecesFemaleGenotypeHumansIndiaInfantMaleMolecular EpidemiologyPrevalenceTertiary Care CentersDiarrheaEnzyme-linked immune-sorbent assay (ELISA)RajasthanRotavirus

Identifiers

PMID33247377
OpenAlexW3106558346

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.