Evidence map›Paper›PMID 33247319›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2021

Male patients with neuromyelitis optica spectrum disorders: different clinical characteristics and worse steroid treatment response.

Rui Li, Cong Li, Zhifeng Mao, Qiao Huang, Yaqing Shu, Yanyu Chang, Jingqi Wang, Yuge Wang, Wei Qiu

Abstract read
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Relapse-related outcomes in the Danish population-based AQP4- antibody seropositive neuromyelitis optica spectrum disorder cohort.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rui Li *Multiple Sclerosis Center, Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou, 510630, Guangdong Province, China.
Cong Li *Multiple Sclerosis Center, Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou, 510630, Guangdong Province, China.
Zhifeng MaoKingMed College of Laboratory Medicine, Guangzhou Medical University, Guangzhou, Guangdong, China.
Qiao HuangThe Second People's Hospital of Zhaoqing, Zhaoqing, China.
Yaqing ShuMultiple Sclerosis Center, Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou, 510630, Guangdong Province, China.
Yanyu ChangMultiple Sclerosis Center, Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou, 510630, Guangdong Province, China.
Jingqi WangMultiple Sclerosis Center, Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou, 510630, Guangdong Province, China.
Yuge WangMultiple Sclerosis Center, Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou, 510630, Guangdong Province, China.
Wei QiuMultiple Sclerosis Center, Department of Neurology, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou, 510630, Guangdong Province, China. qiuwei120@vip.163.com.ORCID http://orcid.org/0000-0002-0880-958X
Sun Yat-sen University · CNKingmed Diagnostics · CNThe First People's Hospital of Zhaoqing · CN

Funding

Guangdong Basic and Applied Basic Research Foundation 2019A1515010297National Natural Science Foundation of China 81771300National Natural Science Foundation of China 81901229National Natural Science Foundation of China 81971140Natural Science Foundation of Guangdong Province 2015A030310149Natural Science Foundation of Guangdong Province 2017A030313853Science and Technology Planning Project of Guangdong Province 201904010444
6 · The paper itself

Abstract

backgroundClinical data on male neuromyelitis optica spectrum (NMO) patients remain limited to date.

objectiveTo analyze clinical characteristics, therapeutic responses, and outcomes in Chinese male NMOSD patients.

methodsWe retrospectively assessed clinical, demographic, treatment, and outcome data of male patients with NMOSD.

resultsWe identified 52 male patients among 471 NMOSD patients. Male patients had more frequent optic neuritis (ON) attacks and less frequent myelitis than female patients. No-remission rates of high-dose intravenous steroid therapy were higher in male patients than in female patients.

conclusionMale NMOSD patients had different clinical characteristics and worse response to high-dose intravenous steroid therapy than female patients.

Indexed as

Neuromyelitis OpticaOptic NeuritisAquaporin 4FemaleHumansMaleRetrospective StudiesSteroidsAquaporin 4SteroidsClinical characteristicsNeuromyelitis optica spectrum disordersSexSteroid treatment

Identifiers

PMID33247319
OpenAlexW3107113660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.