Evidence map›Paper›PMID 33247022›Full record

Observational studyBMJ open2020

Lung volume reduction eligibility in patients with COPD completing pulmonary rehabilitation: results from the UK National Asthma and COPD Audit Programme.

Sara C Buttery, Adam Lewis, Samuel V Kemp, Winston Banya, Jennifer K Quint, Michael C Steiner, Nicholas S Hopkinson

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Observational
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Sara C ButteryNational Heart and Lung Insititute, Imperial College London, London, UK.ORCID 0000-0001-9410-414X
Adam LewisDepartment of Clinical Sciences, Brunel University London, Uxbridge, UK.ORCID 0000-0002-0576-8823
Samuel V KempRespiratory Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
Winston BanyaNational Heart and Lung Insititute, Imperial College London, London, UK.
Jennifer K QuintNational Heart and Lung Insititute, Imperial College London, London, UK.ORCID 0000-0003-0149-4869
Michael C SteinerDepartment of Respiratory Sciences, Leicester Respiratory Biomedical Research Centre, University of Leicester, Leicester, UK.
Nicholas S HopkinsonNational Heart and Lung Insititute, Imperial College London, London, UK n.hopkinson@imperial.ac.uk.ORCID 0000-0003-3235-0454
Lung Institute · USBrunel University of London · GBRoyal Brompton & Harefield NHS Foundation Trust · GBUniversity of Leicester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo establish what proportion of patients completing a UK pulmonary rehabilitation (PR) programme meet the 2018 National Institute for Health and Care Excellence (NICE) chronic obstructive pulmonary disease (COPD) guideline (NG115) criteria to have a respiratory review to establish whether referral to a lung volume reduction multidisciplinary team would be appropriate. This respiratory review would include evaluation of the presence of hyperinflation and the presence of emphysema on CT scan. The NICE criteria include measures of breathlessness and exercise capacity but these parameters are not completely defined.

designObservational study.

settingPR programmes across the UK in 2015 (210 centres) and 2017 (184 centres) entering data into the Royal College of Physicians' National Asthma and COPD Audit Programme.

participants8295 (55.7%) of 14 889 patients in programmes using incremental shuttle walk test (ISWT) or 6-minute walk test (6MWT) as an outcome measure completed PR, and 4856 (32.6%) had complete data recorded (6MWT/ISWT, baseline spirometry, Medical Research Council (MRC) dyspnoea score).

resultsDepending on the walking test safety threshold adopted for the ISWT (≥140 m or ≥ 80 m) and the MRC dyspnoea score threshold used (MRC score ≥3 or ≥4 at the end of PR), between 4.9% and 18.1% of PR completers met the NICE criteria for a lung volume reduction-focused respiratory review.

conclusionsLung volume reduction therapies are beneficial in appropriately selected patients with COPD, but few procedures are performed, and treatment pathways are unclear. These data help to inform the feasibility of the approach recommended by NICE and highlight the need for future systematic pathways to reduce inequalities in patients being considered for effective treatments.

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveAgedExercise ToleranceFemaleHumansMalePneumonectomyUnited Kingdomchronic airways diseaseemphysemaorganisation of health servicesrehabilitation medicine

Identifiers

PMID33247022
PMCPMC7703433
OpenAlexW3108700149

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.