Evidence map›Paper›PMID 33246979›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Diagnostic Performance of PET Versus SPECT Myocardial Perfusion Imaging in Patients with Smaller Left Ventricles: A Substudy of the

René R Sevag Packard, Joel L Lazewatsky, Cesare Orlandi, Jamshid Maddahi

Registry-linked trialOpen access · bronzeAbstract readClinical Trial, Phase IIIComparative Study
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07761728 (Comparative Evaluation of 18F-Flurpiridaz and 82Rb-Chloride PET Myocardial Perfusion Imaging), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07761728 enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Comparative Evaluation of 18F-Flurpiridaz and 82Rb-Chloride PET Myocardial Perfusion Imaging: The FLARE (Flurpiridaz vs. Rubidium Evaluation) Trial

TypeobservationalSponsorUniversity of California, Los AngelesRan2025 to 2027Enrolled60ConditionsCoronary Artery Disease, Coronary Microvascular Disease
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Comparative evaluation of a novel [European journal of nuclear medicine and molecular imaging · 2025
    Article
  6. The clinical promise ofNature cardiovascular research · 2025
    Article
  7. Recent Progress in Myocardial Perfusion Imaging Techniques.Nuclear medicine and molecular imaging · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Expanding the repertoire ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2024
    Article
  12. Article
  13. Prevalence and nature of extracardiac findings in PET/CT myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  14. Review
  15. Imaging of heart disease in women: review and case presentation.European journal of nuclear medicine and molecular imaging · 2022
    Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

René R Sevag Packard
Joel L LazewatskyLantheus Medical Imaging, North Billerica, Massachusetts; and.
Cesare OrlandiLantheus Medical Imaging, North Billerica, Massachusetts; and.
Jamshid MaddahiDivision of Cardiology, Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California.
Lantheus Medical Imaging (United States) · USUniversity of California, Los Angeles · USWest Los Angeles College · US

Funding

Integrating 3-D Intravascular Sensors with Fractional Flow Reserve for Lipid-Rich PlaquesI01BX004558 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI PACKARD, RENE R.S. · 2020 to 2023
–
BLRD VA I01 BX004558
6 · The paper itself

Abstract

The performance of SPECT myocardial perfusion imaging (MPI) may deteriorate in smaller hearts, primarily because of the lower resolution of conventional Anger cameras.

Indexed as

Myocardial Perfusion ImagingPositron-Emission TomographyPyridazinesTomography, Emission-Computed, Single-PhotonFemaleHeart VentriclesHumansMaleMiddle AgedOrgan SizeBMS 747158-02Pyridazinesdiagnostic performanceflurpiridazleft ventricle sizePET MPISPECT MPI

Identifiers

PMID33246979
PMCPMC8729859
OpenAlexW3107417221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.