ArticleBMC genomics2020
Molecular convergent and parallel evolution among four high-elevation anuran species from the Tibetan region.
Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Adaptive molecular convergence is pervasive across deep time and largely decoupled from phenotypic convergence.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The genetic foundations of convergent traits.Nature reviews. Genetics · 2026Review
- Association analysis and in silico functional predictions of RMDN2 variants in chickens.Animal bioscience · 2026Article
- The Vulpes vulpes montana genome provides insights into high-altitude adaptation mechanisms of the Vulpes species.Communications biology · 2025Article
- A Complete Assembly and Annotation of the American Shad Genome Yields Insights into the Origins of Diadromy.Genome biology and evolution · 2025Article
- Ecological diversification of sea catfishes is accompanied by genome-wide signatures of positive selection.Nature communications · 2024Article
- The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation.BMC genomics · 2024Review
- The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation.bioRxiv : the preprint server for biology · 2024Article
- Selection and Gene Duplication Associated With High-Elevation Diversification in Pristimantis, the Largest Terrestrial Vertebrate Genus.Genome biology and evolution · 2024Article
- Accurate Detection of Convergent Mutations in Large Protein Alignments With ConDor.Genome biology and evolution · 2024Article
- Article
- Convergent Genomic Signatures of Cashmere Traits: Evidence for Natural and Artificial Selection.International journal of molecular sciences · 2023Article
- Convergent Genomic Signatures of High-Altitude Adaptation among Six Independently Evolved Mammals.Animals : an open access journal from MDPI · 2022Article
- Article
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundTo date, evidence for the relative prevalence or rarity of molecular convergent and parallel evolution is conflicting, and understanding of how these processes contribute to adaptation is limited. We compared four high-elevation anuran species (Bufo tibetanus, Nanorana parkeri, Rana kukunoris and Scutiger boulengeri) from the Tibetan region, and examined convergent and parallel amino acid substitutions between them and how they may have contributed to high-elevation adaptation.
resultsGenomic data of the four high-elevation species and eight of their low-elevation close relatives were gathered. A total of 1098 orthologs shared by all species were identified. We first conducted pairwise comparisons using Zhang and Kumar's test. Then, the R
conclusionsThere is a substantial amount of convergent evolution at the amino-acid level among high-elevation amphibians, although these sites are concentrated in a few genes, not widespread across the genomes. This may attribute to the fact that all the target species are from the same environment. The relative prevalence of convergent substitutions among high-elevation amphibians provides an excellent opportunity for further study of molecular convergent evolution.
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