SynthesisEuropean journal of obstetrics, gynecology, and reproductive biology2021
Maternal and perinatal outcomes in pregnant women infected by SARS-CoV-2: A meta-analysis.
Synthesis in European journal of obstetrics, gynecology, and reproductive biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 5 of them syntheses that pooled it.
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Who cites it
71 citing papers in PubMed, 5 syntheses or guidelines pooled it, 157 citations in OpenAlex.
- Perinatal Enterovirus Infection in Neonates: A Systematic Review.Journal of medical virology · 2025Pooled it
- The impact of COVID-19 infections on pregnancy outcomes in women.BMC pregnancy and childbirth · 2024Pooled it
- The prevalence of mental ill-health in women during pregnancy and after childbirth during the Covid-19 pandemic: a systematic review and Meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- [Health impact of COVID pandemic. SESPAS Report 2022].Gaceta sanitaria · 2022Pooled it
- Pooled it
- Trimester of maternal SARS-CoV-2 infection differentially predicts newborn size in the COVID-19 Mother Baby Outcomes (COMBO) cohort.Pediatric research · 2026Article
- Laboratory changes and clinical correlates of disease severity in hospitalized pregnant women with COVID-19.Annals of medicine and surgery (2012) · 2025Article
- Article
- Previous or current infection with SARS-CoV-2 virus and its impact on maternal and neonatal health outcomes in Benin: a sero-epidemiological study in pregnant women.Archives of public health = Archives belges de sante publique · 2025Article
- Comparison of Modified Labor Induction Strategies for Pregnant Women at a Single Tertiary Center Before and During the COVID-19 Pandemic.Diagnostics (Basel, Switzerland) · 2024Article
- Cranial ultrasonographic findings in newborns exposed to SARS-CoV-2: a single-centre cross-sectional analysis.Italian journal of pediatrics · 2024Article
- COVID-19 and pregnancy: a comprehensive study of comorbidities and outcomes.BMC public health · 2024Article
- Prevalence of Thrombocytopenia in Pregnant Women with COVID-19: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Assessing the Impact of Hematological Changes in Pregnancy on Maternal and Fetal Death: A Narrative Review.Cureus · 2024Review
- Article
- The financial burden of SARS-CoV-2 pregnancies in a tertiary exclusive COVID-19 maternity.Journal of medicine and life · 2024Observational
- SARS-CoV-2 infection by trimester of pregnancy and adverse perinatal outcomes: a Mexican retrospective cohort study.BMJ open · 2024Article
- Relationships between Fetal and Neonatal Outcomes and Spectrum of COVID-19 Disease in Pregnant Women.Tanaffos · 2024Article
- Neonatal outcomes of maternal prenatal coronavirus infection.Pediatric research · 2024Review
- Management of neonates with maternal prenatal coronavirus infection and influencing factors.Pediatric research · 2024Review
11 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence concerning coronavirus disease-19 (covid-19) in pregnancy is still scarce and scattered. This meta-analysis aims to evaluate maternal and neonatal outcomes in covid-19 pregnancies and identify factors associated with perinatal viral transmission. Medline, Scopus, CENTRAL, Web of Science and Google Scholar databases were systematically searched to 3 June 2020. Overall, 16 observational studies and 44 case reports/series were included. Fever was the most frequent maternal symptom, followed by cough and shortness of breath, while about 15 % of infected were asymptomatic. Severe disease was estimated to occur in 11 % of women in case reports/series and in 7 % (95 % CI: 4 %-10 %) in observational studies. Two maternal deaths were reported. The rate of neonatal transmission did not differ between women with and without severe disease (OR: 1.94, 95 % CI: 0.50-7.60). Preterm birth occurred in 29.7 % and 16 % (95 % CI: 11 %-21 %) in data obtained from case series and observational studies, respectively. Stillbirth occurred in 3 cases and 2 neonatal deaths were observed. Vertical transmission was suspected in 4 cases. Fever was the most common neonatal symptom (40 %), followed by shortness of breath (28 %) and vomiting (24 %), while 20 % of neonates were totally asymptomatic. In conclusion, the maternal and neonatal clinical course the infection is typically mild, presenting low mortality rates. The risk of vertical transmission is suggested to be low and may not be affected by the severity of maternal disease. Further large-scale studies are needed to clarify the risk factors associated with viral transmission and severe infection in the neonatal population.
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