Evidence map›Paper›PMID 33245845›Full record

ArticleStem cells translational medicine2021

A replicating stem-like cell that contributes to bone morphogenetic protein 2-induced heterotopic bone formation.

Julio Mejia, Elizabeth Salisbury, Corinne Sonnet, Zbigniew Gugala, Elizabeth A Olmsted-Davis, Alan R Davis

Open access · goldAbstract read
In one paragraph

Article in Stem cells translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Julio MejiaCenter for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital, Houston, Texas, USA.
Elizabeth SalisburyDepartment of Orthopedic Surgery and Rehabilitation, University of Texas Medical Branch, Galveston, Texas, USA.
Corinne SonnetCenter for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital, Houston, Texas, USA.
Zbigniew GugalaDepartment of Orthopedic Surgery and Rehabilitation, University of Texas Medical Branch, Galveston, Texas, USA.
Elizabeth A Olmsted-DavisCenter for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital, Houston, Texas, USA.
Alan R DavisCenter for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital, Houston, Texas, USA.ORCID 0000-0001-7469-6205
Methodist Hospital · USTexas Children's Hospital · USThe University of Texas Medical Branch at Galveston · US

Funding

Neural Mechanisms in Heterotopic OssificationR01AR066556 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI DAVIS, ALAN ROBERT · 2014 to 2018
$1.7M
Epigenetic reprogramming to generate novel chondro-osseous stem cells for bone tissue engineeringR21AR077783 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI DAVIS, ALAN ROBERT, DAVIS, ELIZABETH ANN · 2020 to 2021
$382k
NIAMS NIH HHS R01 AR066556NIAMS NIH HHS R21 AR077783
6 · The paper itself

Abstract

Bone morphogenetic protein 2 (BMP2)-induced heterotopic bone formation (HBF) starts synchronously from zero upon BMP2 induction, which is advantageous for lineage tracking. The studies reported here in GLAST-Cre

Indexed as

Bone Morphogenetic Protein 2Ossification, HeterotopicStem CellsAnimalsCell DifferentiationMesenchymal Stem CellsMiceOsteoblastsBone Morphogenetic Protein 2adult stem cellsbonechondrogenesisCre-loxP systemosteoblaststem cell transplantationstem/progenitor cell

Identifiers

PMID33245845
PMCPMC7980206
OpenAlexW3108540554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.