Evidence map›Paper›PMID 33245831›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Fluorescence Assisted Capillary Electrophoresis of Glycans Enabled by the Negatively Charged Auxochromes in 1-Aminopyrenes.

Elizaveta A Savicheva, Jan Seikowski, Jeannette I Kast, Christoph R Grünig, Vladimir N Belov, Stefan W Hell

Open access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Driving the Emission Towards Blue by Controlling the HOMO-LUMO Energy Gap in BFChemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Elizaveta A SavichevaDepartment of Nanobiophotonics, Max Planck Institute for Biophysical Chemistry (MPIBPC), Am Fassberg 11, 37077, Göttingen, Germany.
Jan SeikowskiFacility for Synthetic Chemistry, MPIBPC, Germany.
Jeannette I KastMicrosynth AG, Schützenstrasse 15, 9436, Balgach, Switzerland.
Christoph R GrünigMicrosynth AG, Schützenstrasse 15, 9436, Balgach, Switzerland.
Vladimir N BelovDepartment of Nanobiophotonics, Max Planck Institute for Biophysical Chemistry (MPIBPC), Am Fassberg 11, 37077, Göttingen, Germany.ORCID 0000-0002-7741-4653
Stefan W HellDepartment of Nanobiophotonics, Max Planck Institute for Biophysical Chemistry (MPIBPC), Am Fassberg 11, 37077, Göttingen, Germany.
Max Planck Institute for Biophysical Chemistry · DEMicrosynth (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A compact and negatively charged acceptor group, N-(cyanamino)sulfonyl, is introduced for dye design and its influence on the absorption and emission spectra of the "push-pull" chromophores is demonstrated with 1,3,6-tris[(cyanamino)sulfonyl]-8-aminopyrene. The new sulfonamides, including O-phosphorylated (3-hydroxyazetidine)-N-sulfonyl, are negatively charged electron acceptors and auxochromes. 1-Aminopyrenes decorated with the new sulfonamides have three or six negative charges (pH ≥8), low m/z ratios, high mobilities in an electric field, and yellow to orange emission. We labeled maltodextrin oligomers by reductive amination, separated the products by electrophoresis, and demonstrated their high brightness in a commercial DNA analyzer and the distribution of the emission signal among the detection channels.

Indexed as

chromophoresdonor-acceptor systemselectrophoresisfluorescent probesglycoconjugates

Identifiers

PMID33245831
PMCPMC7898655
OpenAlexW3115178378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.