Evidence map›Paper›PMID 33245500›Full record

ArticleSleep & breathing = Schlaf & Atmung2021

Sleep-disordered breathing in severe mental illness: clinical evaluation of oximetry diagnosis and management limitations.

P Espinel, N Marshall, B J Yee, J Hollis, K Smith, A L D'Rozario, G Gauthier, T Lambert, R R Grunstein

Abstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

P EspinelCIRUS, Centre for Sleep and Chronobiology - NHMRC Centre of Research Excellence, Woolcock Institute of Medical Research, Level 4, 431 Glebe Point Road, Glebe, NSW, 2018, Australia.
N MarshallCIRUS, Centre for Sleep and Chronobiology - NHMRC Centre of Research Excellence, Woolcock Institute of Medical Research, Level 4, 431 Glebe Point Road, Glebe, NSW, 2018, Australia.
B J YeeCIRUS, Centre for Sleep and Chronobiology - NHMRC Centre of Research Excellence, Woolcock Institute of Medical Research, Level 4, 431 Glebe Point Road, Glebe, NSW, 2018, Australia.
J HollisCollaborative Centre for Cardiometabolic Health in Psychosis - Sydney Local Health District, Ground Floor, Clinical Sciences Building, Hospital Road, Concord, NSW, 2139, Australia.
K SmithCollaborative Centre for Cardiometabolic Health in Psychosis - Sydney Local Health District, Ground Floor, Clinical Sciences Building, Hospital Road, Concord, NSW, 2139, Australia.
A L D'RozarioCIRUS, Centre for Sleep and Chronobiology - NHMRC Centre of Research Excellence, Woolcock Institute of Medical Research, Level 4, 431 Glebe Point Road, Glebe, NSW, 2018, Australia.
G GauthierDepartment of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Level 11, 50 Missenden Road, Camperdown, NSW, 2050, Australia.
T LambertCollaborative Centre for Cardiometabolic Health in Psychosis - Sydney Local Health District, Ground Floor, Clinical Sciences Building, Hospital Road, Concord, NSW, 2139, Australia.
R R GrunsteinCIRUS, Centre for Sleep and Chronobiology - NHMRC Centre of Research Excellence, Woolcock Institute of Medical Research, Level 4, 431 Glebe Point Road, Glebe, NSW, 2018, Australia. ron.grunstein@sydney.edu.au.
Royal Prince Alfred Hospital · AUSydney Local Health District · AUUniversity of Sydney · AUWoolcock Institute of Medical Research · AUConcord Repatriation General Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo describe the diagnosis and management pathway of sleep-disordered breathing (SDB) in a sample of patients with severe mental illness (SMI), and to assess the feasibility and patient acceptability of overnight oximetry as a first-step screening method for detecting severe SDB in this population.

methodsThe study was a retrospective audit of patients with SMI seen at a Collaborative Centre for Cardiometabolic Health in Psychosis service who were invited for overnight oximetry between November 2015 and May 2018. The adjusted oxygen desaturation index (ODI) was calculated using 4% desaturation criteria. Results were discussed with a sleep specialist and categorized into a 4-level risk probability tool for SDB.

resultsOf 91 adults consenting for overnight oximetry, 90 collected some oximetry data, though 11 of these 90 patients collected technically unsatisfactory oximetry. Thus 79/90 patients (88%) collected adequate oximetry data for at least one night. The oximetry traces suggested likely minimal obstructive sleep apnea (OSA) in 41 cases, moderate to severe OSA in 25 patients, severe OSA in 9 patients and possible obesity hypoventilation syndrome (OHS) in 4 cases. Full polysomnography was recommended for 39 patients but only one-third underwent testing. Nineteen patients were reviewed by a sleep specialist. Of the 10 patients who initiated CPAP, four were considered adherent to treatment.

conclusionHome oximetry may be a pragmatic option for SDB screening in patients with SMI but reliable full diagnostic and management pathways need to be developed.

Indexed as

OximetryAdolescentAdultFeasibility StudiesFemaleHumansMaleMass ScreeningMental DisordersMiddle AgedPatient Acceptance of Health CarePatient AcuityRetrospective StudiesSleep Apnea, ObstructiveYoung AdultClinical auditObstructive sleep apneaOximetrySchizophreniaSevere mental illnessSleep-disordered breathing

Identifiers

PMID33245500
OpenAlexW3107740715

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.