ArticlePediatric surgery international2021
Predictive factors for the development of postoperative Hirschsprung-associated enterocolitis in children operated during infancy.
Article in Pediatric surgery international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Prevalence of Hirschsprung-associated enterocolitis in patients with Hirschsprung disease.Pediatric surgery international · 2022Pooled it
- Bowel function at preschool and early childhood age in children with long-segment Hirschsprung disease.European journal of pediatrics · 2023Trial
- Age and seasonality in Hirschsprung-associated enterocolitis risk: a longitudinal cohort study.Pediatric surgery international · 2026Article
- Histochemical characterization of muscularis macrophage loss and disruption of a miR-93-5p-AHNAK neuro-immune axis in Hirschsprung's disease.Histochemistry and cell biology · 2026Article
- Postoperative Hirschsprung's associated enterocolitis (HAEC): transition zone as putative histopathological predictive factor.Journal of clinical pathology · 2025Article
- Development of a nomogram for predicting postoperative Hirschsprung-associated enterocolitis.Frontiers in pediatrics · 2025Article
- Surgical and clinical determinants of postoperative Hirschsprung-associated enterocolitis: Multivariate analysis in a large cohort.Pediatric discovery · 2024Article
- Paneth-like cells disruption and intestinal dysbiosis in the development of enterocolitis in an iatrogenic rectosigmoid hypoganglionosis rat model.Frontiers in surgery · 2024Article
- Robotic-assisted proctosigmoidectomy for Hirschsprung's disease: A multicenter prospective study.World journal of gastroenterology · 2023Article
- Update on the Pathogenesis of the Hirschsprung-Associated Enterocolitis.International journal of molecular sciences · 2023Review
- Prognostic factors of postoperative Hirschsprung-associated enterocolitis: a cohort study.Pediatric surgery international · 2023Article
- Risk factors for Hirschsprung-associated enterocolitis following Soave: a retrospective study over a decade.BMC pediatrics · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe risk factors for postoperative Hirschsprung-associated enterocolitis (HAEC) are still incompletely understood, especially age at which surgery is performed. Therefore, the aim of this study was to identify the risk factors for the development of postoperative HAEC in children operated during infancy.
methodsThirty-five children who had undergone radical surgery for Hirschsprung disease (HD) during infancy were included in the study. They were divided into two groups; those who developed postoperative HAEC (HAEC, 14 patients) and those who did not (no HAEC, 21 patients). Their medical records were retrospectively reviewed for clinical details.
resultsDeveloping postoperative HAEC was significantly associated with long-segment HD (p = 0.020) and the age at radical surgery (p = 0.0241). No other factors had a significant association with postoperative HAEC. In the patients who developed postoperative HAEC (n = 14), those with Trisomy 21 had significantly longer hospitalizations than those without. Patients with long-segment HD had a higher hospitalization rate than those with short-segment HD.
conclusionThis study clearly showed that long-segment HD and older age at radical surgery are risk factors for developing postoperative HAEC.
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