Evidence map›Paper›PMID 33245376›Full record

ArticleCancer immunology, immunotherapy : CII2021

Anti-PD-1 antibody-mediated activation of type 17 T-cells undermines checkpoint blockade therapy.

Qingsheng Li, Phuong T Ngo, Nejat K Egilmez

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Targeted lungScience advances · 2026
    Article
  2. Review
  3. Review
  4. Pulmonary toxicity of immune checkpoint immunotherapy.The Journal of clinical investigation · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Qingsheng LiDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, 505 S. Hancock St., Louisville, KY, 40202, USA. qingsheng.li@louisville.edu.
Phuong T NgoDepartment of Medicine, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.
Nejat K EgilmezDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, 505 S. Hancock St., Louisville, KY, 40202, USA. nejat.egilmez@louisville.edu.ORCID http://orcid.org/0000-0002-2544-2767
University of Louisville · US

Funding

U.S. Department of Defense W81XWH1610185U.S. Department of Defense W81XWH1910265
6 · The paper itself

Abstract

Tumors that develop in the genetic LSL-K-ras

Indexed as

Drug Resistance, NeoplasmAnimalsAntibodies, MonoclonalCarcinoma, Non-Small-Cell LungHumansLung NeoplasmsLymphocyte ActivationMiceProgrammed Cell Death 1 ReceptorTh17 CellsT-LymphocytesT-Lymphocytes, CytotoxicTumor Cells, CulturedAntibodies, MonoclonalPDCD1 protein, humanProgrammed Cell Death 1 ReceptorAnti-PD-1CD4 T-cellCheckpoint blockade resistanceIL-17NSCLCTh17 cell

Identifiers

PMID33245376
PMCPMC10991855
OpenAlexW3109001488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.