Evidence map›Paper›PMID 33245053›Full record

ArticlePhysics in medicine and biology2020

Body morphometry appropriate computational phantoms for dose and risk optimization in pediatric renal imaging with Tc-99m DMSA and Tc-99m MAG3.

Justin L Brown, Briana Sexton-Stallone, Ye Li, Eric C Frey, S Ted Treves, Frederic H Fahey, Donika Plyku, Xinhua Cao, George Sgouros, Wesley E Bolch

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. MIRD Pamphlet No. 28, Part 1: MIRDcalc-A Software Tool for Medical Internal Radiation Dosimetry.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Justin L BrownJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611-6131, United States of America.ORCID 0000-0002-3099-1998
Briana Sexton-StalloneDepartment of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States of America.ORCID 0000-0002-2660-780X
Ye LiDepartment of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, United States of America.ORCID 0000-0001-5620-4246
Eric C FreyDepartment of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, United States of America.ORCID 0000-0002-9596-3955
S Ted TrevesDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America.ORCID 0000-0002-1029-196X
Frederic H FaheyDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States of America.ORCID 0000-0003-1738-9254
Donika PlykuThe Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States of America.ORCID 0000-0001-7305-8834
Xinhua CaoDepartment of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States of America.ORCID 0000-0002-7011-0171
George SgourosThe Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States of America.ORCID 0000-0002-4553-2866
Wesley E BolchJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611-6131, United States of America.ORCID 0000-0002-7175-9968

Funding

Dose Reduction in Pediatric Molecular ImagingR01EB013558 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI FREY, ERIC C., SGOUROS, GEORGE · 2012 to 2020
$4.6M
NIBIB NIH HHS R01 EB013558
6 · The paper itself

Abstract

Current guidelines for administered activity (AA) in pediatric nuclear medicine imaging studies are based on a 2016 harmonization of the 2010 North American Consensus guidelines and the 2007 European Association of Nuclear Medicine pediatric dosage card. These guidelines assign AA scaled to patient body mass, with further constraints on maximum and minimum values of radiopharmaceutical activity. These guidelines, however, are not formulated based upon a rigor-ous evaluation of diagnostic image quality. In a recent study of the renal cortex imaging agent

Indexed as

Phantoms, ImagingTechnetium Tc 99m Dimercaptosuccinic AcidTechnetium Tc 99m MertiatideAdolescentChildChild, PreschoolDiagnostic ImagingFemaleHumansInfantInfant, NewbornKidneyMaleMonte Carlo MethodRisk AssessmentTechnetium Tc 99m Dimercaptosuccinic AcidTechnetium Tc 99m Mertiatide

Identifiers

PMID33245053
PMCPMC13374500

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.