Evidence map›Paper›PMID 33244995›Full record

ReviewCNS oncology2020

Intermixed arteriovenous malformation and hemangioblastoma: case report and literature review.

Vincent Healy, Philip J O'Halloran, Mohammed B Husien, Ciaran Bolger, Michael Farrell

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in CNS oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vincent HealyDepartment of Neurosurgery, Beaumont Hospital, Dublin, Ireland.
Philip J O'HalloranDepartment of Neurosurgery, Beaumont Hospital, Dublin, Ireland.
Mohammed B HusienDepartment of Neurosurgery, Beaumont Hospital, Dublin, Ireland.
Ciaran BolgerDepartment of Neurosurgery, Beaumont Hospital, Dublin, Ireland.
Michael FarrellDepartment of Neurosurgery, Beaumont Hospital, Dublin, Ireland.
Beaumont Hospital · IERoyal College of Surgeons in Ireland · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the third presentation of an intermixed arteriovenous malformation and hemangioblastoma. The rare occurrence of the diagnostic histologic features of both a neoplasm and vascular malformation in a single lesion is more common in gliomas, as angioglioma, and is termed an 'intermixed' lesion. We review the literature concerning the developmental biology of each lesion, and potential interplay in the formation of an intermixed vascular neoplasm and vascular malformation. The roles of cellular origin, genetic susceptibility, favourable microenvironment, altered local gene expression and key regulatory pathways are reviewed. Our review supports angiography and genetic profiling in intermixed lesions to inform management strategies. Consideration should be given to multimodality therapeutic interventions as required, including microsurgical resection, stereotactic radiosurgery and further research to exploit emerging molecular targets.

Indexed as

Arteriovenous MalformationsCerebellar NeoplasmsHemangioblastomaHumansMaleMiddle Agedarteriovenous malformationhemangioblastomaintermixed

Identifiers

PMID33244995
PMCPMC7737198
OpenAlexW3106599913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.