Evidence map›Paper›PMID 33244918›Full record

ArticleJournal of biomedical optics2020

Handheld optical coherence tomography for clinical assessment of dental plaque and gingiva.

Jungeun Won, Pin-Chieh Huang, Darold R Spillman, Eric J Chaney, Ralf Adam, Malgorzata Klukowska, Ronit Barkalifa, Stephen A Boppart

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Heliyon · 2023
    Article
  10. Use of Optical Coherence Tomography in Dentistry.International journal of dentistry · 2023
    Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jungeun WonUniversity of Illinois Urbana-Champaign, Beckman Institute for Advanced Science and Technology, Urba, United States.
Pin-Chieh HuangUniversity of Illinois Urbana-Champaign, Beckman Institute for Advanced Science and Technology, Urba, United States.
Darold R SpillmanUniversity of Illinois Urbana-Champaign, Beckman Institute for Advanced Science and Technology, Urba, United States.
Eric J ChaneyUniversity of Illinois Urbana-Champaign, Beckman Institute for Advanced Science and Technology, Urba, United States.
Ralf AdamProcter & Gamble Company, Clinical Operations, German Innovation Center, Kronberg, Germany.
Malgorzata KlukowskaProcter & Gamble Company, Oral Health Science Center, Mason, Ohio, United States.
Ronit BarkalifaUniversity of Illinois Urbana-Champaign, Beckman Institute for Advanced Science and Technology, Urba, United States.
Stephen A BoppartUniversity of Illinois Urbana-Champaign, Beckman Institute for Advanced Science and Technology, Urba, United States.
University of Illinois Urbana-Champaign · USProcter & Gamble (Switzerland) · CHProcter & Gamble (United States) · USZero to Three · US

Funding

Partnership for Primary Care Imaging of the EarR01EB013723 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2011 to 2018
$6.4M
Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis MediaR01EB028615 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A, MAHADEVAN-JANSEN, ANITA · 2019 to 2022
$2.5M
Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor MarginsR01CA213149 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2017 to 2021
$2.4M
NCI NIH HHS R01 CA213149NIBIB NIH HHS R01 EB013723NIBIB NIH HHS R01 EB028615
6 · The paper itself

Abstract

significanceOptical coherence tomography (OCT) offers high spatial resolution and contrast for imaging intraoral structures, yet few studies have investigated its clinical feasibility for dental plaque and gingiva imaging in vivo. Furthermore, the accessibility is often limited to anterior teeth due to bulky imaging systems and probes.

aimA custom-designed, handheld probe-based, spectral-domain OCT system with an interchangeable attachment was developed to assess dental plaque and gingival health in a clinical setting. APPROACH: Healthy volunteers and subjects with gingivitis and sufficient plaque were recruited. The handheld OCT system was operated by trained dental hygienists to acquire images of dental plaque and gingiva at various locations and after one-week use of oral hygiene products.

resultsThe handheld OCT can access premolars, first molars, and lingual sides of teeth to visualize the plaque distribution. OCT intensity-based texture analysis revealed lower intensity from selected sites in subjects with gingivitis. The distribution of the dental plaque after one-week use of the oral hygiene products was compared, showing the capability of OCT as a longitudinal tracking tool.

conclusionsOCT has a strong potential to display and assess dental plaque and gingiva in a clinical setting. Meanwhile, technological challenges remain to perform systematic longitudinal tracking and comparative analyses.

Indexed as

Dental PlaqueGingivitisGingivaHumansMolarTomography, Optical Coherencebiofilmdental plaquegingivaoptical coherence tomographyoral cavity

Identifiers

PMID33244918
PMCPMC7690845
OpenAlexW3110327117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.