ArticleAndrologia2021
Investigation of SARS-CoV-2 in semen samples and the effects of COVID-19 on male sexual health by using semen analysis and serum male hormone profile: A cross-sectional, pilot study.
Article in Andrologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 11 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
86 citing papers in PubMed, 11 syntheses or guidelines pooled it, 152 citations in OpenAlex.
- Pooled it
- The Effect of COVID-19 on Male Sex Hormones: A Meta-Analysis of Prospective Cohort Study.Journal of epidemiology and global health · 2024Pooled it
- Systematic review and meta-analysis of serum total testosterone and luteinizing hormone variations across hospitalized Covid-19 patients.Scientific reports · 2024Pooled it
- SARS-CoV-2 impairs male fertility by targeting semen quality and testosterone level: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Semen parameters and sex hormones as affected by SARS-CoV-2 infection: A systematic review.Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie · 2022Pooled it
- Andrological effects of SARS-Cov-2 infection: a systematic review and meta-analysis.Journal of endocrinological investigation · 2022Pooled it
- SARS-CoV-2 effects on sperm parameters: a meta-analysis study.Journal of assisted reproduction and genetics · 2022Pooled it
- Associations between COVID-19 infection and sex steroid hormones.Frontiers in endocrinology · 2022Pooled it
- Absence of SARS-CoV-2 infection in the semen of men recovering from COVID-19 infection: An exploratory study and review of literature.Andrologia · 2021Pooled it
- Effect of COVID-19 on Male Reproductive System - A Systematic Review.Frontiers in endocrinology · 2021Pooled it
- Urological complications of COVID-19: a systematic review.International braz j urol : official journal of the Brazilian Society of UrologyPooled it
- Divergent long-term trends in semen quality and reproductive hormones across the COVID-19 pandemic era in infertile men: an age-stratified retrospective study.Basic and clinical andrology · 2026Article
- Alterations in Semen Quality and Immune-Related Factors in Men with Infertility who Recovered from COVID-19.MedComm · 2025Article
- SARS-CoV-2 in semen: a multicenter prospective study and literature review.Basic and clinical andrology · 2024Article
- Quantitative Proteomics of COVID-19 Recovered Patients Identifies Long-Term Changes in Sperm Proteins Leading to Cellular Stress in Spermatozoa.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Does COVID-19 affect sperm quality in males? the answer may be yes, but only temporarily.Virology journal · 2024Article
- Article
- Investigating the mode of transmission of COVID-19 through genital secretions, semen, the birth canal, and lactation: A systematic review.Journal of education and health promotion · 2024Article
- A Scientometric Evaluation of COVID-19 and Male Reproductive Research.Clinics and practice · 2023Article
- The Effect of SARS-Cov2 Infection on The Spermogram: A Prospective Study.International journal of fertility & sterility · 2023Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
The study investigated whether there is a male reproductive system coronavirus disease-2019 (COVID-19) phenomenon. Thirty participants who met the inclusion criteria were enrolled in the study between April and May 2020. The participants were assigned in one of the three groups including COVID-19 patients before and after treatment, and controls. Presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within the semen samples was investigated. Additionally, participant's demographics, semen parameters and serum sex hormone levels were compared between the groups. SARS-CoV-2 was not detected within the semen samples. Sperm morphology and serum sex hormone levels were significantly different between the groups. In the post hoc analysis, sperm morphology was significantly lower in the COVID-19 patients. Patients before treatment had significantly lower serum FSH, LH and T levels than controls. However, patients after treatment had similar serum FSH, LH and T levels with controls and patients before treatment. In our opinion, COVID-19 and its treatment had no specific deteriorative effect on male sexual health at a short-time period. In the patients before treatment, decreased serum of T, FSH and LH levels was consistent with acute patient stress due to COVID-19. Similarly, it seems that decreased sperm morphology was associated with the acute fever.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.