Evidence map›Paper›PMID 33244598›Full record

ArticleThe Journal of nutrition2021

Linear Growth Trajectories in Early Childhood and Adult Cognitive and Socioemotional Functioning in a Guatemalan Cohort.

María J Ramírez-Luzuriaga, John Hoddinott, Reynaldo Martorell, Shivani A Patel, Manuel Ramírez-Zea, Rachel Waford, Aryeh D Stein

Open access · hybridAbstract read
In one paragraph

Article in The Journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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  5. Household behavior and vulnerability to acute malnutrition in Kenya.Humanities & social sciences communications · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

María J Ramírez-LuzuriagaNutrition and Health Science Program, Laney Graduate School, Emory University, Atlanta, GA, USA.
John HoddinottDivision of Nutritional Sciences and Charles H. Dyson School of Applied Economics and Management, Cornell University, Ithaca, NY, USA.
Reynaldo MartorellNutrition and Health Science Program, Laney Graduate School, Emory University, Atlanta, GA, USA.
Shivani A PatelNutrition and Health Science Program, Laney Graduate School, Emory University, Atlanta, GA, USA.
Manuel Ramírez-ZeaINCAP Research Center for the Prevention of Chronic Diseases, Institute of Nutrition of Central America and Panama, Guatemala City, Guatemala.
Rachel WafordNutrition and Health Science Program, Laney Graduate School, Emory University, Atlanta, GA, USA.
Aryeh D SteinNutrition and Health Science Program, Laney Graduate School, Emory University, Atlanta, GA, USA.
Emory University · USCornell University · USInstitute of Nutrition of Central America and Panama · GT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGrowth faltering in early childhood is associated with poor human capital attainment, but associations of linear growth in childhood with executive and socioemotional functioning in adulthood are understudied.

objectivesIn a Guatemalan cohort, we identified distinct trajectories of linear growth in early childhood, assessed their predictors, and examined associations between growth trajectories and neurodevelopmental outcomes in adulthood. We also assessed the mediating role of schooling on the association of growth trajectories with adult cognitive outcomes.

methodsIn 2017-2019, we prospectively followed 1499 Guatemalan adults who participated in a food supplementation trial in early childhood (1969-1977). We derived height-for-age sex-specific growth trajectories from birth to 84 mo using latent class growth analysis.

resultsWe identified 3 growth trajectories (low, intermediate, high) with parallel slopes and intercepts already differentiated at birth in both sexes. Children of taller mothers were more likely to belong to the high and intermediate trajectories [relative risk ratio (RRR): 1.21; 95% CI: 1.15, 1.26, and RRR: 1.11; 95% CI: 1.07, 1.15, per 1-cm increase in height, respectively] compared with the low trajectory. Children in the wealthiest compared with the poorest socioeconomic tertile were more likely to belong to the high trajectory compared with the low trajectory (RRR: 2.24; 95% CI: 1.29, 3.88). In males, membership in the high compared with low trajectory was positively associated with nonverbal fluid intelligence, working memory, inhibitory control, and cognitive flexibility at ages 40-57 y. Sex-adjusted results showed that membership in the high compared with low trajectory was positively associated with meaning and purpose scores at ages 40-57 y. Associations of intermediate compared with low growth trajectories with study outcomes were also positive but of lesser magnitude. Schooling partially mediated the associations between high and intermediate growth trajectories and measures of cognitive ability in adulthood.

conclusionsModifiable and nonmodifiable risk factors predicted growth throughout childhood. Membership in the high and intermediate growth trajectories was positively associated with adult cognitive and socioemotional functioning.

Indexed as

Child DevelopmentCognitionSocial BehaviorAdultChildChild, PreschoolCohort StudiesFemaleFood SupplyHumansInfantInfant, NewbornMaleSocial EnvironmentSocioeconomic Factorsexecutive functionlatent class growth analysislinear growth trajectoriesnonverbal fluid intelligencesocioemotional functioning

Identifiers

PMID33244598
PMCPMC7779237
OpenAlexW3108986256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.