ArticleThe journal of nutrition, health & aging2020
Age-Related Frailty: A Clinical Model for Geroscience?
Article in The journal of nutrition, health & aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Frailty and Fitness in Older Adults With Acute Myeloid Leukemia: From Chronological Age to Multiparametric Assessment.European journal of haematology · 2026Review
- Frailty, physiological reserve, and surgical resilience: toward a dynamic stress-recovery model.Aging clinical and experimental research · 2026Review
- What emergency department length of stay reveals about aging-related vulnerability and declining resilience.GeroScience · 2026Article
- Intrinsic capacity in Lewy body dementia: a review.The Journal of frailty & aging · 2025Review
- Association of health promotion behaviors with frailty in Chinese middle-aged and older adults: a cross-sectional study.BMC geriatrics · 2025Article
- Frailty and Survivability of Polish Caucasian Nonagenarians and Centenarians.Geriatrics (Basel, Switzerland) · 2024Article
- Frailty indices based on self-report, blood-based biomarkers and examination-based data in the Canadian Longitudinal Study on Aging.Age and ageing · 2022Article
- Physiological Systems in Promoting Frailty.Comprehensive Physiology · 2022Review
- Frailty and Associated Factors among Chinese Centenarians.The journal of nutrition, health & aging · 2022Article
- Symptoms and experiences of frailty in lung cancer patients with chemotherapy: A mixed-method approach.Frontiers in oncology · 2022Article
- Biomarkers of Age-Related Frailty and Frailty Related to Diseases: An Exploratory, Cross-Sectional Analysis from the MAPT Study.The journal of nutrition, health & aging · 2022Article
- Frailty and the risk of dementia: is the association explained by shared environmental and genetic factors?BMC medicine · 2021Article
- Decreased Mortality in 1-Year Survivors of Umbilical Cord Blood Transplant vs. Matched Related or Matched Unrelated Donor Transplant in Patients with Hematologic Malignancies.Transplantation and cellular therapy · 2021Article
- Proteomics and Epidemiological Models of Human Aging.Frontiers in physiology · 2021Review
- Editorial: COVID19 Vaccination in Frail People. Lots of Hope and Some Questions.The journal of nutrition, health & aging · 2021Article
- Metabolomics-Based Frailty Biomarkers in Older Chinese Adults.Frontiers in medicine · 2021Article
- Editorial: Physical Frailty: A Biological Marker of Aging?The journal of nutrition, health & aging · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In their everyday practice, geriatricians are confronted with the fact that older age and multimorbidity are associated to frailty. Indeed, if we take the example of a very old person with no diseases that progressively becomes frail with no other explanation, there is a natural temptation to link frailty to aging. On the other hand, when an old person with a medical history of diabetes, arthritis and congestive heart failure becomes frail there appears an obvious relationship between frailty and comorbidity. The unsolved question is: Considering that frailty is multifactorial and in the majority of cases comorbidity and aging are acting synergistically, can we disentangle the main contributor to the origin of frailty: disease or aging? We believe that it is important to be able to differentiate age-related frailty from frailty related to comorbidity. In fact, with the emergence of geroscience, the physiopathology, diagnosis, prognosis and treatment will probably have to be different in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.