Evidence map›Paper›PMID 33244466›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Study of the Effect of Treatment With Atrial Natriuretic Peptide (ANP) and Cinaciguat in Chronic Hypoxic Neonatal Lambs on Residual Strain and Microstructure of the Arteries.

Alvaro Navarrete, Zhuoming Chen, Pedro Aranda, Daniel Poblete, Andrés Utrera, Claudio M García-Herrera, Alejandro Gonzalez-Candia, Felipe A Beñaldo, German Ebensperger, Roberto V Reyes and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Alvaro NavarreteDepartamento de Ingeniería Mecánica, Universidad de Santiago de Chile, Santiago, Chile.
Zhuoming ChenDepartamento de Ingeniería Mecánica, Universidad de Santiago de Chile, Santiago, Chile.
Pedro ArandaDepartamento de Ingeniería Mecánica, Universidad de Santiago de Chile, Santiago, Chile.
Daniel PobleteDepartamento de Ingeniería Mecánica, Universidad de Santiago de Chile, Santiago, Chile.
Andrés UtreraDepartamento de Ingeniería Mecánica, Universidad de Santiago de Chile, Santiago, Chile.
Claudio M García-HerreraDepartamento de Ingeniería Mecánica, Universidad de Santiago de Chile, Santiago, Chile.
Alejandro Gonzalez-CandiaInstituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua, Chile.
Felipe A BeñaldoPathophysiology Program, Faculty of Medicine, Institute of Biomedical Sciences (ICBM), Universidad de Chile, Santiago, Chile.
German EbenspergerPathophysiology Program, Faculty of Medicine, Institute of Biomedical Sciences (ICBM), Universidad de Chile, Santiago, Chile.
Roberto V ReyesPathophysiology Program, Faculty of Medicine, Institute of Biomedical Sciences (ICBM), Universidad de Chile, Santiago, Chile.
Emilio A HerreraPathophysiology Program, Faculty of Medicine, Institute of Biomedical Sciences (ICBM), Universidad de Chile, Santiago, Chile.
Anibal J LlanosPathophysiology Program, Faculty of Medicine, Institute of Biomedical Sciences (ICBM), Universidad de Chile, Santiago, Chile.
Universidad de Santiago de Chile · CLUniversity of Chile · CLUniversity of O'Higgins · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we assessed the effects of Atrial Natriuretic Peptide (ANP) and Cinaciguat, as experimental medicines to treat neonatal lambs exposed to chronic hypoxic conditions. To compare the different treatments, the mechanical responses of aorta, carotid, and femoral arterial walls were analyzed by means of axial pre-stretch and ring-opening tests, through a study with

Indexed as

chronic hypoxiahistologypre-stretching testpulmonary hypertensionresidual deformationring opening test

Identifiers

PMID33244466
PMCPMC7683788
OpenAlexW3102502990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.