Evidence map›Paper›PMID 33244300›Full record

ArticleFrontiers in pharmacology2020

Rejuveinix Shows a Favorable Clinical Safety Profile in Human Subjects and Exhibits Potent Preclinical Protective Activity in the Lipopolysaccharide-Galactosamine Mouse Model of Acute Respiratory Distress Syndrome and Multi-Organ Failure.

Fatih M Uckun, James Carlson, Cemal Orhan, Joy Powell, Natalie M Pizzimenti, Hendrik van Wyk, Ibrahim H Ozercan, Michael Volk, Kazim Sahin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Regulation of inflammatory lung injury and repair by transforming growth factors.American journal of physiology. Lung cellular and molecular physiology · 2025
    Review
  2. Review
  3. Article
  4. RJX Improves Wound Healing in Diabetic Rats.Frontiers in endocrinology · 2022
    Article
  5. Article
  6. Review
  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fatih M UckunDrug Discovery Program, Reven Pharmaceuticals, Golden, CO, United States.
James CarlsonDrug Discovery Program, Reven Pharmaceuticals, Golden, CO, United States.
Cemal OrhanDepartment of Animal Nutrition, Faculty of Veterinary, Firat University, Elazig, Turkey.
Joy PowellDrug Discovery Program, Reven Pharmaceuticals, Golden, CO, United States.
Natalie M PizzimentiDrug Discovery Program, Reven Pharmaceuticals, Golden, CO, United States.
Hendrik van WykDrug Discovery Program, Reven Pharmaceuticals, Golden, CO, United States.
Ibrahim H OzercanDepartment of Pathology Faculty of Medicine, Firat University, Elazig, Turkey.
Michael VolkDrug Discovery Program, Reven Pharmaceuticals, Golden, CO, United States.
Kazim SahinDepartment of Animal Nutrition, Faculty of Veterinary, Firat University, Elazig, Turkey.
Fırat University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute lung injurycancerCOVID-19cytokine release syndromemulti-organ dysfunctionpneumoniasepsis

Identifiers

PMID33244300
PMCPMC7683794
OpenAlexW3098425747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.