Evidence map›Paper›PMID 33244206›Full record

ArticleWorld journal of gastroenterology2020

Third-look endoscopy prevents delayed bleeding after endoscopic submucosal dissection under antithrombotic therapy.

Ryosuke Ikeda, Kingo Hirasawa, Chiko Sato, Yuichiro Ozeki, Atsushi Sawada, Masafumi Nishio, Takehide Fukuchi, Ryosuke Kobayashi, Makomo Makazu, Masataka Taguri and 1 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. [Research Progress in Delayed Bleeding after Endoscopic Submucosal Dissection of Early-Stage Gastrointestinal Cancer].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ryosuke IkedaEndoscopy Division, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Kingo HirasawaEndoscopy Division, Yokohama Medical University Center Hospital, Yokohama 232-0024, Japan. kingo-h@urahp.yokohama-cu.ac.jp.
Chiko SatoEndoscopy Division, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Yuichiro OzekiEndoscopy Division, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Atsushi SawadaEndoscopy Division, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Masafumi NishioEndoscopy Division, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Takehide FukuchiEndoscopy Division, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Ryosuke KobayashiEndoscopy Division, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Makomo MakazuEndoscopy Division, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Masataka TaguriDepartment of Data Science, Yokohama City University School of Data Science, Yokohama 236-0004, Japan.
Shin MaedaDivision of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.
Yokohama City University Medical Center · JPYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative delayed bleeding (PDB) after gastric endoscopic submucosal dissection (ESD) is the most common adverse event in patients receiving antithrombotics even with second-look endoscopy. Moreover, with the increasing prevalence of cardiovascular and cerebrovascular diseases in an aging population with associated lifestyle-related diseases, an increasing number of patients receive antithrombotics. Several attempts have been made to prevent PDB in aging population; however, a consensus has yet to be reached.

aimTo examine the efficacy of third-look endoscopy (TLE) for PDB prevention.

methodsOne hundred patients with early gastric neoplasms receiving antithrombotics were prospectively enrolled and subjected to ESD with TLE between February 2017 and July 2019. The primary endpoint was PDB rate, which was compared with our preset threshold. Furthermore, we divided the bleeding period into early-and late-onset PDB (E-PDB and L-PDB, respectively) and analyzed its rate. As a secondary analysis, we compared PDB rates with those of a historical control group, using propensity score matching, and calculated the PDB rates per antithrombotic agent use in each group.

resultsIn total, 96 patients and 114 specimens were finally evaluated. The overall PDB rate was 7.9% (9/114) [90%CI: 4.7-13.1,

conclusionTLE for gastric ESD reduces overall PDB, and especially L-PDB incidence, among patients receiving antithrombotics.

Indexed as

Endoscopic Mucosal ResectionStomach NeoplasmsAgedEndoscopyFibrinolytic AgentsGastric MucosaGastroscopyHumansPostoperative HemorrhageRetrospective StudiesFibrinolytic AgentsAntithrombotic agentsEndoscopic submucosal dissectionLate phase bleedingPhase IIPostoperative delayed bleedingThird look endoscopy

Identifiers

PMID33244206
PMCPMC7656207
OpenAlexW3095115409

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.