Evidence map›Paper›PMID 33244120›Full record

ArticleScientific reports2020

Effect of different levels of hydrolysable tannin intake on the reproductive hormones and serum biochemical indices in healthy female rats.

Faiza Manzoor, Mahr Un Nisa, Hafiz Amjad Hussain, Nazir Ahmad, Huma Umbreen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  5. Effects of dietary supplementation with microencapsulatedFrontiers in veterinary science · 2023
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  7. Frontiers in pharmacology · 2022
    Article
  8. Effects ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Faiza ManzoorFaculty of Life Sciences, Institute of Home and Food Sciences, Government College University, Faisalabad, 38000, Punjab, Pakistan.
Mahr Un NisaFaculty of Life Sciences, Institute of Home and Food Sciences, Government College University, Faisalabad, 38000, Punjab, Pakistan.
Hafiz Amjad HussainDepartment of Internal Medicine, Faisalabad Medical University, Faisalabad, 38000, Punjab, Pakistan.
Nazir AhmadFaculty of Life Sciences, Institute of Home and Food Sciences, Government College University, Faisalabad, 38000, Punjab, Pakistan. drnazirahmad@gcuf.edu.pk.
Huma UmbreenFaculty of Life Sciences, Institute of Home and Food Sciences, Government College University, Faisalabad, 38000, Punjab, Pakistan.
Government College University, Faisalabad · PKPunjab Medical College · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present work aimed to find out the effect of different levels of hydrolysable tannin (HT) on serum hormonal profile, biochemical indices, lipid profile, apparent digestibility of nutrients and body weight gain in healthy female rats. Forty five adult healthy female rats of 8 weeks old were randomly divided into five equal groups. Different doses of HT 0, 0.5, 1, 1.5 and 2% were administered daily to each rats group on the body weight basis for 6 weeks. The results had shown the reduction trend (p < 0.05) in the blood glucose, serum cholesterol, low density lipoprotein, testosterone, prolactin, ghrelin, total oxidative stress and serum iron levels; while an improvement (p < 0.05) was seen in serum follicle stimulating hormone, progesterone, luteinizing hormone, high density lipoprotein, IgM and total antioxidant capacity. However, no effect (p > 0.05) was noticed in serum IgG, protein, estrogen and calcium levels. A significant reduction (p < 0.05) was seen in the apparent nutrient digestibility and body weight gain. The results had shown improvement in the feed conversion ratio (p < 0.05) but non-significant decrease (p > 0.05) in the feed intake. The findings showed that HT had healthy effects on the serum biochemical indices and reproductive hormonal profile but had a negative impact on the nutrient digestibility. Thus, the study concluded that HT could be used as an herbal medicine for the treatment of leading metabolic and infertility diseases like obesity and polycystic ovarian syndrome in females.

Indexed as

AnimalsBlood GlucoseBody WeightCholesterolEstrogensFemaleFollicle Stimulating HormoneGonadal Steroid HormonesLipoproteins, LDLLuteinizing HormoneProgesteroneProlactinRatsRats, WistarTanninsTestosteroneBlood GlucoseCholesterolEstrogensFollicle Stimulating HormoneGonadal Steroid HormonesLipoproteins, LDLLuteinizing HormoneProgesteroneProlactinTanninsTestosterone

Identifiers

PMID33244120
PMCPMC7692459
OpenAlexW3109372841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.