Evidence map›Paper›PMID 33244095›Full record

ArticleScientific reports2020

TRPM2 promotes autophagic degradation in vascular smooth muscle cells.

Qiannan Zhao, Jingxuan Li, Wing-Hung Ko, Yiu-Wa Kwan, Liwen Jiang, Lei Sun, Xiaoqiang Yao

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Transient receptor potential channels inChannels (Austin, Tex.) · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Roles of TRPM channels in glioma.Cancer biology & therapy · 2024
    Review
  11. Review
  12. Review
  13. Unbalanced Redox With Autophagy in Cardiovascular Disease.Journal of lipid and atherosclerosis · 2023
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. The Role of TRPM2 in Endothelial Function and Dysfunction.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qiannan ZhaoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People's Republic of China.
Jingxuan LiSchool of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People's Republic of China.
Wing-Hung KoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People's Republic of China.
Yiu-Wa KwanSchool of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People's Republic of China.
Liwen JiangCentre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, People's Republic of China.
Lei SunSchool of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People's Republic of China. lilysun20@gzhmu.edu.cn.
Xiaoqiang YaoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People's Republic of China. yao2068@cuhk.edu.hk.
Chinese University of Hong Kong · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient receptor potential channel M2 (TRPM2) is a Ca

Indexed as

AnimalsAutophagyCalciumCalcium SignalingCell DeathCells, CulturedLysosomesMaleMiceMice, Inbred C57BLMice, KnockoutMuscle, Smooth, VascularMyocytes, Smooth MuscleOxidative StressReactive Oxygen SpeciesTRPM Cation ChannelsCalciumReactive Oxygen SpeciesTRPM2 protein, mouseTRPM Cation Channels

Identifiers

PMID33244095
PMCPMC7693237
OpenAlexW3106947165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.