Evidence map›Paper›PMID 33244011›Full record

Observational studyScientific reports2020

Selecting the most important self-assessed features for predicting conversion to mild cognitive impairment with random forest and permutation-based methods.

Jaime Gómez-Ramírez, Marina Ávila-Villanueva, Miguel Ángel Fernández-Blázquez

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jaime Gómez-RamírezInstituto de Salud Carlos III, Centro de Alzheimer Fundación Reina Sofía, Valderrebollo 5, 28031, Madrid, Spain. jd.gomezramirez@gmail.com.
Marina Ávila-VillanuevaInstituto de Salud Carlos III, Centro de Alzheimer Fundación Reina Sofía, Valderrebollo 5, 28031, Madrid, Spain.
Miguel Ángel Fernández-BlázquezInstituto de Salud Carlos III, Centro de Alzheimer Fundación Reina Sofía, Valderrebollo 5, 28031, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's Disease is a complex, multifactorial, and comorbid condition. The asymptomatic behavior in the early stages makes the identification of the disease onset particularly challenging. Mild cognitive impairment (MCI) is an intermediary stage between the expected decline of normal aging and the pathological decline associated with dementia. The identification of risk factors for MCI is thus sorely needed. Self-reported personal information such as age, education, income level, sleep, diet, physical exercise, etc. is called to play a key role not only in the early identification of MCI but also in the design of personalized interventions and the promotion of patients empowerment. In this study, we leverage a large longitudinal study on healthy aging in Spain, to identify the most important self-reported features for future conversion to MCI. Using machine learning (random forest) and permutation-based methods we select the set of most important self-reported variables for MCI conversion which includes among others, subjective cognitive decline, educational level, working experience, social life, and diet. Subjective cognitive decline stands as the most important feature for future conversion to MCI across different feature selection techniques.

Indexed as

AgedAged, 80 and overAlzheimer DiseaseCognitive DysfunctionCohort StudiesDietExerciseFemaleHumansLongitudinal StudiesMachine LearningMaleNeuropsychological TestsRisk FactorsSleepSpain

Identifiers

PMID33244011
PMCPMC7692490

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.