Evidence map›Paper›PMID 33243990›Full record

ArticleNature communications2020

Direct RNA sequencing reveals m

Alexander M Price, Katharina E Hayer, Alexa B R McIntyre, Nandan S Gokhale, Jonathan S Abebe, Ashley N Della Fera, Christopher E Mason, Stacy M Horner, Angus C Wilson, Daniel P Depledge and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 205 citations in OpenAlex.

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  18. Viral Modulation of Host Splicing.Annual review of virology · 2025
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84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Alexander M PriceDivision of Protective Immunity and Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.ORCID 0000-0003-4654-4604
Katharina E HayerDepartment of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.ORCID 0000-0002-1463-3111
Alexa B R McIntyreDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA.
Nandan S GokhaleDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, 27710, USA.
Jonathan S AbebeDepartment of Medicine, New York University School of Medicine, New York, NY, 10017, USA.
Ashley N Della FeraDivision of Protective Immunity and Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
Christopher E MasonDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA.ORCID 0000-0002-1850-1642
Stacy M HornerDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, 27710, USA.ORCID 0000-0002-9351-7409
Angus C WilsonDepartment of Microbiology, New York University School of Medicine, New York, NY, 10017, USA.
Daniel P DepledgeDepartment of Medicine, New York University School of Medicine, New York, NY, 10017, USA. daniel.depledge@nyulangone.org.
Matthew D WeitzmanDivision of Protective Immunity and Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA. weitzmanm@email.chop.edu.ORCID 0000-0001-9713-167X
Children's Hospital of Philadelphia · USNew York University · USCornell University · USDuke Medical Center · USUniversity of Washington · US

Funding

Control of Translation in Herpesvirus Infected Cells - Resubmission - 1R01GM056927 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Ian J Mohr · 1999 to 2026
$7.6M
Defining the role of the RNA modification N6-methyladenosine in the hepatitis C virus lifecycleR01AI125416 · NIAID · DUKE UNIVERSITY · PI Stacy Michelle Horner · 2016 to 2026
$5.5M
Viral modulation of epitranscriptomic mechanismsR01AI118891 · NIAID · WASHINGTON UNIVERSITY · PI GARCIA, BENJAMIN A, WEITZMAN, MATTHEW D. · 2015 to 2025
$5.4M
Viral Modulation of Genetic StabilityR01CA097093 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI WEITZMAN, MATTHEW D. · 2003 to 2019
$5.2M
Virus Host Interactions that Regulate Translation in Cells Infected with HSV-1R01AI073898 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MOHR, IAN J · 2008 to 2020
$5.0M
Training In Tumor VirologyT32CA115299 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ROBERTSON, ERLE S. · 2006 to 2021
$4.7M
Double-stranded RNA during DNA virus infectionR01AI145266 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI WEITZMAN, MATTHEW D. · 2019 to 2023
$3.0M
EPITRANSCRIPTOMIC REGULATION OF CYTOMEGALOVIRUS INFECTIONR01AI152543 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DEPLEDGE, DANIEL PEARCE, MOHR, IAN J · 2020 to 2025
$2.7M
Adenovirus manipulation of cellular chromatin to overcome host responsesR01AI121321 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI WEITZMAN, MATTHEW D. · 2018 to 2022
$2.7M
Quantitative mass spectrometry for comprehending epigenetic mechanisms in a new underlying neurological developmental disorderR01HD106051 · NICHD · WASHINGTON UNIVERSITY · PI Benjamin A Garcia · 2022 to 2026
$2.6M
Viral manipulation of neuronal microRNAs to maintain trophic support and HSV latencyR21AI147163 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WILSON, ANGUS C · 2019 to 2020
$475k
Mapping the RNA modification N6-methyladenosine during Zika virus infectionR21AI129851 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI HORNER, STACY MICHELLE, MASON, CHRISTOPHER EDWARD · 2017 to 2018
$469k
NCI NIH HHS R01 CA097093NCI NIH HHS T32 CA115299NIAID NIH HHS F32 AI138432NIAID NIH HHS R01 AI073898NIAID NIH HHS R01 AI118891NIAID NIH HHS R01 AI121321NIAID NIH HHS R01 AI125416NIAID NIH HHS R01 AI145266NIAID NIH HHS R01 AI152543NIAID NIH HHS R21 AI129851NIAID NIH HHS R21 AI130618NIAID NIH HHS R21 AI147163NICHD NIH HHS R01 HD106051NIGMS NIH HHS R01 GM056927
6 · The paper itself

Abstract

Adenovirus is a nuclear replicating DNA virus reliant on host RNA processing machinery. Processing and metabolism of cellular RNAs can be regulated by METTL3, which catalyzes the addition of N6-methyladenosine (m

Indexed as

RNA SplicingA549 CellsAdenosineAdenoviruses, HumanAdenovirus Infections, HumanDNA, ViralGene Knockdown TechniquesGene Knockout TechniquesHEK293 CellsHost-Pathogen InteractionsHumansMethyltransferasesRNA, Small InterferingRNA, ViralSequence Analysis, RNAVirus ReplicationAdenosineDNA, ViralMethyltransferasesMETTL3 protein, humanN-methyladenosineRNA, Small InterferingRNA, Viral

Identifiers

PMID33243990
PMCPMC7691994
OpenAlexW3107659143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.