Evidence map›Paper›PMID 33243763›Full record

ArticleBMJ military health2023

Allocation of funding into blast injury-related research and blast traumatic brain injury between 2000 and 2019: analysis of global investments from public and philanthropic funders.

J W Denny, R J Brown, M G Head, J Batchelor, A S Dickinson

Abstract read
In one paragraph

Article in BMJ military health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Blast Injuries.Advances and technical standards in neurosurgery · 2026
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J W DennyBioengineering Science Research Group, School of Engineering, University of Southampton, Southampton, UK Jack.Denny@soton.ac.uk.ORCID http://orcid.org/0000-0003-3181-4747
R J BrownClinical Informatics Research Unit, University of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0001-5825-6859
M G HeadClinical Informatics Research Unit, University of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0003-1189-0531
J BatchelorClinical Informatics Research Unit, University of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0002-5307-552X
A S DickinsonBioengineering Science Research Group, School of Engineering, University of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0002-9647-1944

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is little systematic tracking or detailed analysis of investments in research and development for blast injury to support decision-making around research future funding.

methodsThis study examined global investments into blast injury-related research from public and philanthropic funders across 2000-2019. Research databases were searched using keywords, and open data were extracted from funder websites. Data collected included study title, abstract, award amount, funder and year. Individual awards were categorised to compare amounts invested into different blast injuries, the scientific approaches taken and analysis of research investment into blast traumatic brain injury (TBI).

resultsA total of 806 awards were identified into blast injury-related research globally, equating to US$902.1 million (m, £565.9m GBP). There was a general increase in year-on-year investment between 2003 and 2009 followed by a consistent decline in annual funding since 2010. Pre-clinical research received $671.3 m (74.4%) of investment. Brain-related injury research received $427.7 m (47.4%), orthopaedic injury $138.6 m (15.4%), eye injury $63.7 m (7.0%) and ear injury $60.5m (6.7%). Blast TBI research received a total investment of $384.3 m, representing 42.6% of all blast injury-related research. The U.S. Department of Defense funded $719.3 m (80%).

conclusionsInvestment data suggest that blast TBI research has received greater funding than other blast injury health areas. The funding pattern observed can be seen as reactive, driven by the response to the War on Terror, the rising profile of blast TBI and congressionally mandated research.

Indexed as

Biomedical ResearchBlast InjuriesBrain Injuries, TraumaticFund RaisingHumansInvestmentsaccident and emergency medicineepidemiologyneurological injuryorthopaedic and trauma surgerytrauma management

Identifiers

PMID33243763
PMCPMC10176327

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.