ArticleBMC infectious diseases2020
A case report of the differential diagnosis of Cellulosimicrobium cellulans-infected endocarditis combined with intracranial infection by conventional blood culture and second-generation sequencing.
Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Human Cellulosimicrobium Infections: A Clinically Oriented Review of Diagnostic and Therapeutic Challenges.Cureus · 2026Review
- Application of a comprehensive approach to pathogen screening in a stowaway rat on an airplane.Scientific reports · 2025Article
- Cellulosimicrobium cellulans endocarditis: a challenge for detection and treatment in interdisciplinary teams.Infection · 2025Article
- Review
- Antimicrobial-Resistant Bacteria from Free-Living Green Turtles (Antibiotics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCellulosimicrobium cellulans is a gram-positive filamentous bacterium found primarily in soil and sewage that rarely causes human infection, especially in previously healthy adults, but when it does, it often indicates a poor prognosis. CASE PRESENTATION: We report a case of endocarditis and intracranial infection caused by C. cellulans in a 52-year-old woman with normal immune function and no implants in vivo. The patient started with a febrile headache that progressed to impaired consciousness after 20 days, and she finally died after treatment with vancomycin combined with rifampicin. C. cellulans was isolated from her blood cultures for 3 consecutive days after her admission; however, there was only evidence of C. cellulans sequences for two samples in the second-generation sequencing data generated from her peripheral blood, which were ignored by the technicians. No C. cellulans bands were detected in her cerebrospinal fluid by second-generation sequencing.
conclusionsSecond-generation sequencing seems to have limitations for certain specific strains of bacteria.
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Registered trials
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