ArticleInternational journal of stroke : official journal of the International Stroke Society2021
Impact of multimorbidity on risk and outcome of stroke: Lessons from chronic kidney disease.
Article in International journal of stroke : official journal of the International Stroke Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Heterogeneity in symptom burden and supportive care needs among older adults with ischemic stroke: a cross-sectional study.BMC geriatrics · 2026Article
- Comprehensive Prestroke Risk Factor Control and Functional Outcomes After Acute Ischemic Stroke.Journal of the American Heart Association · 2026Article
- Intrinsic capacity and stroke risk in a multiple cohort study.Nature communications · 2026Article
- Social determinants of stroke prevalence in the United States adults: Analysis of 42 states using behavioral risk factor surveillance system 2022 data.Preventive medicine reports · 2026Article
- Age-specific and time-dependent trends in health-related quality of life after minor stroke: results of a cross-sectional cohort study.BMJ neurology open · 2026Article
- Safety and Effectiveness of Early Rehabilitation in Patients With Stroke and Concomitant Kidney Disease: A Cohort Study With Claims Data.Archives of rehabilitation research and clinical translation · 2025Article
- The Impact of Concurrent Chronic Heart Failure and Chronic Kidney Dysfunction on Post-Stroke Rehabilitation Outcomes.Neurology international · 2025Article
- Article
- Profile and Prognostic Impact of Multimorbidity in Elderly Patients with Heart Failure: Are there Differences between Men and Women?Current heart failure reports · 2024Review
- Accelerometer-Measured Behavior Patterns in Incident Cerebrovascular Disease: Insights for Preventative Monitoring From the UK Biobank.Journal of the American Heart Association · 2024Article
- Role of Sodium-Glucose Co-Transporter 2 Inhibitors in Chronic Kidney Disease, Congestive Heart Failure and Stroke-A Review and Clinical Guide for Healthcare Professionals.Journal of clinical medicine · 2023Review
- From Kidney Protection to Stroke Prevention: The Potential Role of Sodium Glucose Cotransporter-2 Inhibitors.International journal of molecular sciences · 2022Article
- Latent profile analysis of emergency department presentation characteristics in patients with acute ischemic stroke.Frontiers in neurologyArticle
- Comparing stroke rehabilitation inpatients and clinical trials eligibility criteria: A secondary chart review analysis revealing that most patients could have been excluded from rehabilitation trials based on comorbidity status.Journal of multimorbidity and comorbidityArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
With both an aging population and greater post-stroke survival, multimorbidity is a growing healthcare challenge, affecting over 40% of stroke patients, and rising rapidly and predictably with increasing age. Commonly defined as the co-occurrence of two or more chronic conditions, multimorbidity burden is a strong adverse prognostic factor, associated with greater short- and long-term stroke mortality, worse rehabilitation outcomes, and reduced use of secondary prevention. Chronic kidney disease can be considered as the archetypal comorbidity, being age-dependent and also affecting about 40% of stroke patients. Chronic kidney disease and stroke share very similar traditional cardiovascular risk factor profiles such as hypertension and diabetes, though novel chronic kidney disease-specific risk factors such as inflammation and oxidative stress have also been proposed. Using chronic kidney disease as an exemplar condition, we explore the mechanisms of risk in multimorbidity, implications for management, impact on stroke severity, and downstream consequences such as post-stroke cognitive impairment and dementia.
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