ArticleAnaesthesiology intensive therapy2020
Vitamin D serum levels in multiorgan failure critically ill patients undergoing continuous renal replacement therapies.
Article in Anaesthesiology intensive therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02414386 (Serum Vitamin D Levels in Multi-organ Failure Critically Ill Patients Undergoing Regional Citrate Anticoagulation Continuous Renal Replacement Therapies - Prospective Observational Case-control Study), which is not on this map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Serum Vitamin D Levels in Multi-organ Failure Critically Ill Patients Undergoing Regional Citrate Anticoagulation Continuous Renal Replacement Therapies - Prospective Observational Case-control Study
Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Vitamin D and metabolic bone disease in prolonged continuous kidney replacement therapy: a prospective observational study.BMC nephrology · 2024Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSevere vitamin D deficiency in critically ill patients is linked to mortality. There are no scientific data regarding vitamin D status in critically ill patients undergoing continuous renal replacement therapies. MATERIAL AND
methodsWe aimed to measure vitamin D serum levels in critically ill patients with multi-organ failure undergoing continuous renal replacement therapies. Vitamin D serum measurements in 12-hour time intervals were performed in 20 patients undergoing continuous renal replacement therapies through continuous veno-venous haemodiafiltration (the study group). The results were then compared with the historical control group (20 patients without renal replacement therapy).
resultsIn the control group the median vitamin D level initially decreased, then stabilised around the fourth and fifth measurement, after which it appeared to increase unevenly. In the study group the median vitamin D level decreased considerably, and then stabilised around the third measurement. Although the differences between groups gradually increased for the last three measurements, there was insufficient evidence to indicate that they were statistically significant (P > 0.05). Significant correlations were found between the time of measurement and the level of vitamin D in the study (R = -0.31, P = 0.0002) and control groups (R = -0.18, P = 0.0341).
conclusionsVitamin D serum levels decline rapidly during the course of critical illness in patients undergoing continuous renal replacement therapies. No statistically significant differences in the levels of vitamin D between the study and control groups were found.
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