ArticleEuropean journal of dentistry2021
Biomimetic Mechanism of Action of Fluoridated Toothpaste Containing Proprietary REFIX Technology on the Remineralization and Repair of Demineralized Dental Tissues: An In Vitro Study.
Article in European journal of dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The trial behind it
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Who cites it
14 citing papers in PubMed.
- Lessening the erosive influence of electrolyte sports drinks on teeth using L-arginine and aqueous Miswak extract.Head & face medicine · 2025Trial
- Enamel Remineralizing Agents: State of the Art.Materials (Basel, Switzerland) · 2026Review
- Bovine Teeth as Substitutes for Human Teeth in Dental Research: Ultrastructural and Radiographic Analysis.European journal of dentistry · 2026Article
- Retention of fluoride in the oral cavity: A randomized clinical study with nanoencapsulated fluoride toothpaste.Journal of clinical and experimental dentistry · 2026Review
- Synergistic effects of bioactive silica and fluoride in enamel protection and repair: an in vitro study.Brazilian dental journal · 2026Article
- Innovative dentifrices based on bioactive silica for enamel remineralization and erosion control: an in vitro study.BMC oral health · 2025Article
- Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study.Journal of clinical and experimental dentistry · 2024Article
- Chemical and Ultrastructural Characterization of Dentin Treated with Remineralizing Dentifrices.Journal of functional biomaterials · 2024Article
- Laboratory evaluation of anti-plaque and remineralization efficacy of sugarless probiotic jelly candy supplemented with natural nano prebiotic additive.Scientific reports · 2023Article
- Regenerative and Protective Effects on Dental Tissues of a Fluoride-Silicon-Rich Toothpaste Associated with a Calcium Booster: AnDentistry journal · 2023Article
- Biomimetic approaches and materials in restorative and regenerative dentistry: review article.BMC oral health · 2023Review
- Effectiveness of fluoride-containing toothpastes associated with different technologies to remineralize enamel after pH cycling: an in vitro study.BMC oral health · 2022Article
- Effectiveness of Experimental Whitening Toothpastes Containing Colorants on the Optical Properties of Enamel.TheScientificWorldJournal · 2022Article
- Resistance against Erosive Challenge of Dental Enamel Treated with 1,450-PPM Fluoride Toothpastes Containing Different Biomimetic Compounds.European journal of dentistry · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis MATERIALS AND
methodsBovine enamel blocks (
resultsThe toothpaste with REFIX technology remineralized and repaired the surface enamel effectively. The elemental analysis also demonstrated that treating the enamel with the toothpaste formed a silicon-enriched mineral layer on the enamel surface. Elemental analysis of the enamel cross-sections showed that the toothpaste induced a mineral change. The results were also consistent in the dentin, where the dentinal tubules were progressively occluded until there was complete occlusion after 7 days.
conclusionsWe prove the biomimetic mechanism of action of fluoridated toothpaste containing proprietary REFIX technology for obtaining silicon-enriched, remineralized and repaired dental tissues.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.