Evidence map›Paper›PMID 33242256›Full record

ArticleThe British journal of radiology2021

A study of using a deep learning image reconstruction to improve the image quality of extremely low-dose contrast-enhanced abdominal CT for patients with hepatic lesions.

Le Cao, Xiang Liu, Jianying Li, Tingting Qu, Lihong Chen, Yannan Cheng, Jieliang Hu, Jingtao Sun, Jianxin Guo

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Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

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45citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Le CaoDepartment of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi province, PR China.
Xiang LiuDepartment of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi province, PR China.
Jianying LiGE Healthcare, Computed Tomography Research Center, Beijing, China.
Tingting QuDepartment of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi province, PR China.
Lihong ChenDepartment of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi province, PR China.
Yannan ChengDepartment of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi province, PR China.
Jieliang HuDepartment of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi province, PR China.
Jingtao SunDepartment of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi province, PR China.
Jianxin GuoDepartment of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi province, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the feasibility of using deep learning image reconstruction (DLIR) to significantly reduce radiation dose and improve image quality in contrast-enhanced abdominal CT.

methodsThis was a prospective study. 40 patients with hepatic lesions underwent abdominal CT using routine dose (120kV, noise index (NI) setting of 11 with automatic tube current modulation) in the arterial-phase (AP) and portal-phase (PP), and low dose (NI = 24) in the delayed-phase (DP). All images were reconstructed at 1.25 mm thickness using ASIR-V at 50% strength. In addition, images in DP were reconstructed using DLIR in high setting (DLIR-H). The CT value and standard deviation (SD) of hepatic parenchyma, spleen, paraspinal muscle and lesion were measured. The overall image quality includes subjective noise, sharpness, artifacts and diagnostic confidence were assessed by two radiologists blindly using a 5-point scale (1, unacceptable and 5, excellent). Dose between AP and DP was compared, and image quality among different reconstructions were compared using SPSS20.0.

resultsCompared to AP, DP significantly reduced radiation dose by 76% (0.76 ± 0.09 mSv

conclusionDLIR-H significantly reduces image noise and generates images with clinically acceptable quality and diagnostic confidence with 76% dose reduction. ADVANCES IN KNOWLEDGE: (1) DLIR-H yielded a significantly lower image noise, higher CNR and higher overall image quality score and diagnostic confidence than the ASIR-V50% under low signal conditions. (2) Our study demonstrated that at 76% lower radiation dose, the DLIR-H DP images had similar overall image quality to the routine-dose ASIR-V50% AP images.

Indexed as

Contrast MediaDeep LearningAdultAgedAged, 80 and overFemaleHumansLiverLiver NeoplasmsMaleMiddle AgedProspective StudiesRadiation DosageRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsContrast Media

Identifiers

PMID33242256
PMCPMC7934287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.