Evidence map›Paper›PMID 33242204›Full record

ReviewLa Radiologia medica2021

Severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), influenza, and COVID-19, beyond the lungs: a review article.

Alecio F Lombardi, Amir M Afsahi, Amit Gupta, Ali Gholamrezanezhad

Open access · bronzeAbstract readReview
In one paragraph

Review in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Respiratory Emergencies in Disasters: A Narrative Review.Thoracic research and practice · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Selective Degradation and Inhibition of SARS-CoV-2 3CLInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Exploring Radiologists' Burnout in the COVID-19 Era: A Narrative Review.International journal of environmental research and public health · 2023
    Review
  17. Review
  18. Review
  19. Immunotherapy Assessment: A New Paradigm for Radiologists.Diagnostics (Basel, Switzerland) · 2023
    Review
  20. COVID-19: Has the Liver Been Spared?International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Alecio F Lombardi *Department of Radiology, University of California, San Diego, CA, USA.
Amir M Afsahi *Department of Radiology, University of California, San Diego, CA, USA.
Amit GuptaDepartment of Radiology, Case Western Reserve University, Cleveland, OH, USA.
Ali GholamrezanezhadDepartment of Radiology, Keck School of Medicine, University of Southern California (USC), 1500 San Pablo Street, Health Sciences Campus, Los Angeles, CA, USA. Ali.Gholamrezanezhad@med.ucsd.edu.ORCID http://orcid.org/0000-0001-6930-4246
University of California San Diego · USCase Western Reserve University · USUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the past 20 years four major viral infectious diseases outbreaks caused hundreds of thousands of deaths worldwide: SARS, Influenza H1N1, MERS, and COVID-19. They all present clinically initially as upper and lower respiratory tract infections and may progress to multi-organ failure.

methodsThis study was a systematic review of literature conducted in September 2020 to study extra-pulmonary complications of SARS, FLU, MERS, and current COVID-19. We carried out a systematic search using the keywords in online databases of PubMed, EMBASE, and Google Scholar until June 2020.

objectiveThis article aims to review the most common extra-pulmonary manifestations of SARS, Influenza, MERS, and COVID-19. DISCUSSION: Several studies have reported extra-pulmonary conditions in patients diagnosed with SARS, Influenza, MERS, and COVID-19, either by direct viral injury or from the systemic response to the initial infection.

conclusionSARS, Influenza, MERS, and COVID-19 have all been associated with dysfunction of kidneys, endocrine system, neuromuscular symptoms, perinatal complications, and myocardial injury. Progression from pulmonary disease to a systemic condition has a poor outcome and can result in multi-organ failure.

Indexed as

Acute Kidney InjuryCardiovascular DiseasesCoronavirus InfectionsCOVID-19Disease ProgressionHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanLiver DiseasesMultiple Organ FailureMuscular DiseasesNervous System DiseasesSARS-CoV-2Severe Acute Respiratory SyndromeComplicationsCOVID-19Extra-pulmonaryFLUMERSPneumoniaSARS

Identifiers

PMID33242204
PMCPMC7689190
OpenAlexW3107240951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.