Evidence map›Paper›PMID 33242095›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2021

Association of β-Lactam Allergy Documentation and Prophylactic Antibiotic Use in Surgery: A National Cross-Sectional Study of Hospitalized Patients.

Christie M Bertram, Michael Postelnick, Christian M Mancini, Xiaoqing Fu, Yuqing Zhang, Lucas T Schulz, Tanaya Bhowmick, Francesca Lee, Kimberly G Blumenthal

Open access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Perioperative cefazolin prophylaxis in patients with β-lactam allergy: a quality improvement project.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Drug allergy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Review
  8. A call to address penicillin allergy labels in patients with hematopoietic stem cell transplants: How to avoid rash decisions.Transplant infectious disease : an official journal of the Transplantation Society · 2024
    Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

Christie M BertramNorthwestern Memorial Hospital, Department of Pharmacy, Chicago, Illinois, USA.
Michael PostelnickNorthwestern Memorial Hospital, Department of Pharmacy, Chicago, Illinois, USA.
Christian M ManciniDivision of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Xiaoqing FuDivision of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Yuqing ZhangThe Mongan Institute, Massachusetts General Hospital, Boston, Massachusetts, USA.
Lucas T SchulzDepartment of Pharmacy, University of Wisconsin Health, Madison, Wisconsin, USA.
Tanaya BhowmickDivision of Allergy, Immunology, and Infectious Diseases, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Francesca LeeDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kimberly G BlumenthalDivision of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Massachusetts General Hospital · USBoston University · USHarvard University · USNorthwestern Memorial Hospital · USRosalind Franklin University of Medicine and Science · USRutgers, The State University of New Jersey · USThe University of Texas Southwestern Medical Center · USUniversity of Wisconsin Health · US

Funding

The Clinical and Economic Impact of Penicillin AllergyK01AI125631 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI BLUMENTHAL, KIMBERLY GOLD · 2016 to 2021
$779k
NIAID NIH HHS K01 AI125631
6 · The paper itself

Abstract

Alternative antibiotics for surgical prophylaxis are associated with increased adverse events and surgical site infection compared to cefazolin. In a sample of perioperative inpatients from 100 hospitals in the United States, cefazolin was 9-fold less likely to be used in patients with a documented β-lactam allergy whereas clindamycin was 45-fold more likely.

Indexed as

beta-LactamsDrug HypersensitivityAnti-Bacterial AgentsAntibiotic ProphylaxisCross-Sectional StudiesDocumentationHumansRetrospective StudiesSurgical Wound InfectionUnited StatesAnti-Bacterial Agentsbeta-Lactamsallergyantibioticsurgical prophylaxisβ-lactam

Identifiers

PMID33242095
PMCPMC13370434
OpenAlexW3110155153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.